Glycobiology, 2002, 12(8):463-472

Identification and characterization of a new family of C-type lectin-like genes from planaria Girardia tigrina

A novel family of C-type lectin-like genes, denoted multi-domain free lectin (MDFL), was identified in the freshwater planaria Girardia (Dugesia) tigrina. We cloned several genes that encode proteins comprising a signal peptide and a number of consecutive C-type lectin-like domains (CTLDs) interconnected by short linker stretches. Analyses of genomic organization, CTLD amino acid sequences, and the overall architecture of these proteins indicate that planarian proteins are a separate family of C-type lectin-like proteins. These genes are expressed in specifically differentiated gland cells of planaria and the corresponding proteins are excreted as components of the planarian body surface mucus.

IBCH: 1615
Ссылка на статью в журнале: https://academic.oup.com/glycob/article-lookup/doi/10.1093/glycob/cwf056
Кол-во цитирований на 02.2024: 26
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