Nano-sized melphalan and sarcolysine drug delivery systems: Synthesis and prospects of application
The results of experimental studies concerned with the development of nano-sized drug delivery systems for the antitumour drugs sarcolysine and melphalan are generalized. The structures and biological activities of nanocarriers in comparison with unmodified drugs are discussed. Particular attention is given to the liposomes containing lipid derivatives of sarcolysine and melphalan in the lipid bilayer. The bibliography includes 196 references. © 2013 Russian Academy of Sciences and Turpion Ltd.