Dmitry A. Bolotin


Research fellow (Laboratory of immunosequencing methods)

Phone: +7 (499) 742-81-22

E-mail: bolotin.dmitriy@gmail.com

Selected publications

  1. Izraelson M, Nakonechnaya TO, Moltedo B, Egorov ES, Kasatskaya SA, Putintseva EV, Mamedov IZ, Staroverov DB, Shemiakina II, Zakharova MY, Davydov AN, Bolotin DA, Shugay M, Chudakov DM, Rudensky AY, Britanova OV (2017). Comparative analysis of murine T-cell receptor repertoires. Immunology 153 (2), 133–144
  2. Bolotin DA, Poslavsky S, Davydov AN, Frenkel FE, Fanchi L, Zolotareva OI, Hemmers S, Putintseva EV, Obraztsova AS, Shugay MA, Ataullakhanov RI, Rudensky AY, Schumacher TN, Chudakov DM (2017). Antigen receptor repertoire profiling from RNA-seq data. Nat Biotechnol 35 (10), 908–911
  3. Shagin DA, Turchaninova MA, Shagina IA, Shugay M, Zaretsky AR, Zueva OI, Bolotin DA, Lukyanov S, Chudakov DM (2017). Application of nonsense-mediated primer exclusion (NOPE) for preparation of unique molecular barcoded libraries. BMC Genomics 18 (1), 440
  4. Turchaninova MA, Davydov A, Britanova OV, Shugay M, Bikos V, Egorov ES, Kirgizova VI, Merzlyak EM, Staroverov DB, Bolotin DA, Mamedov IZ, Izraelson M, Logacheva MD, Kladova O, Plevova K, Pospisilova S, Chudakov DM (2016). High-quality full-length immunoglobulin profiling with unique molecular barcoding. Nat Protoc 11 (9), 1599–1616
  5. Britanova OV, Shugay M, Merzlyak EM, Staroverov DB, Putintseva EV, Turchaninova MA, Mamedov IZ, Pogorelyy MV, Bolotin DA, Izraelson M, Davydov AN, Egorov ES, Kasatskaya SA, Rebrikov DV, Lukyanov S, Chudakov DM (2016). Dynamics of individual T Cell repertoires: From cord blood to centenarians. J Immunol 196 (12), 5005–5013
  6. Sarkisyan KS, Bolotin DA, Meer MV, Usmanova DR, Mishin AS, Sharonov GV, Ivankov DN, Bozhanova NG, Baranov MS, Soylemez O, Bogatyreva NS, Vlasov PK, Egorov ES, Logacheva MD, Kondrashov AS, Chudakov DM, Putintseva EV, Mamedov IZ, Tawfik DS, Lukyanov KA, Kondrashov FA (2016). Local fitness landscape of the green fluorescent protein. Nature 533 (7603), 397–401
  7. Nazarov VI, Pogorelyy MV, Komech EA, Zvyagin IV, Bolotin DA, Shugay M, Chudakov DM, Lebedev YB, Mamedov IZ (2015). tcR: An R package for T cell receptor repertoire advanced data analysis. BMC Bioinformatics 16 (1), 175
  8. Shugay M, Bagaev DV, Turchaninova MA, Bolotin DA, Britanova OV, Putintseva EV, Pogorelyy MV, Nazarov VI, Zvyagin IV, Kirgizova VI, Kirgizov KI, Skorobogatova EV, Chudakov DM (2015). VDJtools: Unifying Post-analysis of T Cell Receptor Repertoires. PLoS Comput Biol 11 (11), e1004503
  9. Poslavsky S, Bolotin D (2015). Redberry: A computer algebra system designed for tensor manipulation. J Phys Conf Ser 608 (1),
  10. Bolotin DA, Poslavsky S, Mitrophanov I, Shugay M, Mamedov IZ, Putintseva EV, Chudakov DM (2015). MiXCR: Software for comprehensive adaptive immunity profiling. Nat Methods 12 (5), 380–381
  11. Egorov ES, Merzlyak EM, Shelenkov AA, Britanova OV, Sharonov GV, Staroverov DB, Bolotin DA, Davydov AN, Barsova E, Lebedev YB, Shugay M, Chudakov DM (2015). Quantitative profiling of immune repertoires for minor lymphocyte counts using unique molecular identifiers. J Immunol 194 (12), 6155–6163
  12. Zvyagin IV, Pogorelyy MV, Ivanova ME, Komech EA, Shugay M, Bolotin DA, Shelenkov AA, Kurnosov AA, Staroverov DB, Chudakov DM, Lebedev YB, Mamedov IZ (2014). Distinctive properties of identical twins' TCR repertoires revealed by high-throughput sequencing. Proc Natl Acad Sci U S A 111 (16), 5980–5985
  13. Britanova OV, Putintseva EV, Shugay M, Merzlyak EM, Turchaninova MA, Staroverov DB, Bolotin DA, Lukyanov S, Bogdanova EA, Mamedov IZ, Lebedev YB, Chudakov DM (2014). Age-Related decrease in TCR repertoire diversity measured with deep and normalized sequence profiling. J Immunol 192 (6), 2689–2698
  14. Shugay M, Britanova OV, Merzlyak EM, Turchaninova MA, Mamedov IZ, Tuganbaev TR, Bolotin DA, Staroverov DB, Putintseva EV, Plevova K, Linnemann C, Shagin D, Pospisilova S, Lukyanov S, Schumacher TN, Chudakov DM (2014). Towards error-free profiling of immune repertoires. Nat Methods 11 (6), 653–655
  15. Mamedov IZ, Britanova OV, Zvyagin IV, Turchaninova MA, Bolotin DA, Putintseva EV, Lebedev YB, Chudakov DM (2013). Preparing unbiased T-cell receptor and antibody cDNA libraries for the deep next generation sequencing profiling. Front Immunol 4 (0), 456
  16. Shugay M, Bolotin DA, Putintseva EV, Pogorelyy MV, Mamedov IZ, Chudakov DM (2013). Huge overlap of individual TCR beta repertoires. Front Immunol 4 (0), 466
  17. Putintseva EV, Britanova OV, Staroverov DB, Merzlyak EM, Turchaninova MA, Shugay M, Bolotin DA, Pogorelyy MV, Mamedov IZ, Bobrynina V, Maschan M, Lebedev YB, Chudakov DM (2013). Mother and child T cell receptor repertoires: Deep profiling study. Front Immunol 4 (0), 463
  18. Linnemann C, Heemskerk B, Kvistborg P, Kluin RJC, Bolotin DA, Chen X, Bresser K, Nieuwland M, Schotte R, Michels S, Gomez-Eerland R, Jahn L, Hombrink P, Legrand N, Shu CJ, Mamedov IZ, Velds A, Blank CU, Haanen JBAG, Turchaninova MA, Kerkhoven RM, Spits H, Hadrup SR, Heemskerk MHM, Blankenstein T, Chudakov DM, Bendle GM, Schumacher TNM (2013). High-throughput identification of antigen-specific TCRs by TCR gene capture. Nat Med 19 (11), 1534–1541
  19. Bolotin DA, Shugay M, Mamedov IZ, Putintseva EV, Turchaninova MA, Zvyagin IV, Britanova OV, Chudakov DM (2013). MiTCR: Software for T-cell receptor sequencing data analysis. Nat Methods 10 (9), 813–814
  20. Turchaninova MA, Britanova OV, Bolotin DA, Shugay M, Putintseva EV, Staroverov DB, Sharonov G, Shcherbo D, Zvyagin IV, Mamedov IZ, Linnemann C, Schumacher TN, Chudakov DM (2013). Pairing of T-cell receptor chains via emulsion PCR. Eur J Immunol 43 (9), 2507–2515
  21. Kurnosov AA, Ustyugova SV, Pogorelyy MV, Komkov AY, Bolotin DA, Khodosevich KV, Mamedov IZ, Lebedev YB (2013). A novel approach to identification of somatic retroelements' insertions in human genome. Russ. J. Bioorganic Chem. 39 (4), 417–425
  22. Bolotin DA, Mamedov IZ, Britanova OV, Zvyagin IV, Shagin D, Ustyugova SV, Turchaninova MA, Lukyanov S, Lebedev YB, Chudakov DM (2012). Next generation sequencing for TCR repertoire profiling: Platform-specific features and correction algorithms. Eur J Immunol 42 (11), 3073–3083
  23. Britanova OV, Bochkova AG, Staroverov DB, Fedorenko DA, Bolotin DA, Mamedov IZ, Turchaninova MA, Putintseva EV, Kotlobay AA, Lukyanov S, Novik AA, Lebedev YB, Chudakov DM (2012). First autologous hematopoietic SCT for ankylosing spondylitis: A case report and clues to understanding the therapy. Bone Marrow Transplant 47 (11), 1479–1481
  24. Mishina NM, Bogeski I, Bolotin DA, Hoth M, Niemeyer BA, Schultz C, Zagaynova EV, Lukyanov S, Belousov VV (2012). Can we see PIP 3 and hydrogen peroxide with a single probe? Antioxid Redox Signal 17 (3), 505–512
  25. Mamedov IZ, Britanova OV, Bolotin DA, Chkalina AV, Staroverov DB, Zvyagin IV, Kotlobay AA, Turchaninova MA, Fedorenko DA, Novik AA, Sharonov GV, Lukyanov S, Chudakov DM, Lebedev YB (2011). Quantitative tracking of T cell clones after haematopoietic stem cell transplantation. EMBO Mol Med 3 (4), 201–207