Epigenetics, 2010, 5(7):569-572

Human non-CG methylation: Are human stem cells plant-like?

Non-CG methylation is well characterized in plants where it appears to play a role in gene silencing and genomic imprinting. Although strong evidence for the presence of non-CG methylation in mammals has been available for some time, both its origin and function remain elusive. In this review we discuss available evidence on non-CG methylation in mammals in light of evidence suggesting that the human stem cell methylome contains significant levels of methylation outside the CG site. © 2010 Landes Bioscience.

Dyachenko OV, Shevchuk TV, Kretzner L, Buryanov YI, Smith SS

IBCH: 136
Ссылка на статью в журнале: http://www.tandfonline.com/doi/abs/10.4161/epi.5.7.12702
Кол-во цитирований на 11.2023: 20
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