Mol Biol (Mosk), 2016, 50(6):906-921

The cause of cancer mutations: Improvable bad life or inevitable stochastic replication errors?

Это дубликат статьи: «The cause of cancer mutations: Improvable bad life or inevitable stochastic replication errors?»

Despite substantial progress in understanding the mechanisms of carcinogenesis and fighting oncology diseases, cancer mortality remains rather high. Therefore, there is a striving to reduce this mortality to the level determined by endogenous biological factors. The review analyzes the mutations that lead to cell malignant transformation and describes the contribution that self-renewal of adult tissues makes to tumorigenesis. Cancer progression is considered as a development of a complicated system where cells mutate, evolve, and are subject to selection. Cancer paradoxes are described in conclusion.

IBCH: 3596
Ссылка на статью в журнале: http://elibrary.ru/item.asp?doi=10.7868/S0026898416060033
Кол-во цитирований на 09.2023: 4
Данные статьи проверены модераторами 2016-11-01