Russ. J. Bioorganic Chem., 2009, 35(1):86-93

Genome similarity of Baikal omul and sig

Two members of the Baikal sig family, a lake sig (Coregonus lavaretus baicalensis Dybovsky) and omul (C. autumnalis migratorius Georgi) are close relatives that diverged from the same ancestor 10-20 thousand years ago. In this work, we studied genomic polymorphism of these two fish species. The method of subtractive hybridization (SH) did not reveal the presence of extended sequences in the sig genome and their absence in the omul genome. All the fragments found by SH corresponded to polymorphic noncoding genome regions varying in single nucleotide polymorphisms (SNPs) and short deletions. Many of them are mapped close to genes of the immune system and have regions identical to the Tc1-like transposons abundant among fish, whose transcription activity may affect the expression of adjacent genes. Thus, we showed for the first time that genetic differences between Baikal sig family members are extremely small and cannot be revealed by the SH method. This is another endorsement of the hypothesis on the close relationship between Baikal sig and omul and their evolutionarily recent divergence from a common ancestor. © 2009 Pleiades Publishing, Ltd.

IBCH: 536
Ссылка на статью в журнале: http://link.springer.com/10.1134/S1068162009010117
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