Лаборатория изотопных методов анализа

Избранные публикации

  1. Dorofeeva LV, Starodumova IP, Krauzova VI, Prisyazhnaya NV, Vinokurova NG, Lysanskaya VY, Tarlachkov SV, Evtushenko LI (2018). Rathayibacter oskolensis sp. Nov., a novel actinobacterium from Androsace Koso-poljanskii Ovcz. (Primulaceae) endemic to the Central Russian Upland. Int J Syst Evol Microbiol 68 (5), 1442–1447
  2. Topolyan AP, Belyaeva MA, Slyundina MS, Ilyushenkova VV, Formanovsky AA, Korshun VA, Borisov RS (2017). A novel trityl/acridine derivatization agent for analysis of thiols by (matrix-assisted)(nanowire-assisted)laser desorption/ionization and electrospray ionization mass spectrometry. Anal Methods 9 (45), 6335–6340
  3. Skoblov MY, Lavrov AV, Bragin AG, Zubtsov DA, Andronova VL, Galegov GA, Skoblov YS (2017). The genome nucleotide sequence of herpes simplex virus 1 strain L2. Russ. J. Bioorganic Chem. 43 (2), 140–142
  4. Averin AS, Kosarsky LS, Tarlachkov SV, Vekhnik VA, Averina IV, Alekseev AE, Fesenko EE, Nakipova OV (2017). The effects of KB-R7943, an inhibitor of reverse Na+/Ca2+exchange, on the force of contraction of papillary muscles in the heart of the ground squirrel Spermophilus undulatus. Biophysics (Oxf) 62 (1), 109–114
  5. Topolyan AP, Strizhevskaya DA, Slyundina MS, Belyaeva MA, Ivanova OM, Korshun VA, Ustinov AV, Mikhura IV, Formanovsky AA, Borisov RS (2016). Tris(2,6-dimethoxyphenyl)methyl carbenium ion as a charge derivatization agent for the analysis of primary amines by MALDI mass spectrometry. J ANAL CHEM+ 71 (14), 1326–1331
  6. Agapova OY, Skoblov YS, Tkachev GA, Mironova NA, Golitsyn SP, Masenko VP, Chazova IE, Zykov KA (2016). Changes in the receptor activity of β2-adrenoreceptors of human T-lymphocytes under the effect of β2-agonists. Mol Biol 50 (6), 880–886
  7. Lapchinskaya OA, Katrukha GS, Gladkikh EG, Kulyaeva VV, Coodan PV, Topolyan AP, Alferova VA, Pogozheva VV, Sukonnikov MA, Rogozhin EA, Prokhorenko IA, Brylev VA, Korolev AM, Slyundina MS, Borisov RS, Serebryakova MV, Shuvalov MV, Ksenofontov AL, Stoyanova LG, Osterman IA, Formanovsky AA, Tashlitsky VN, Baratova LA, Timofeeva AV, Tyurin AP (2016). Investigation of the complex antibiotic INA-5812. Russ. J. Bioorganic Chem. 42 (6), 664–671
  8. Shevchuk TV, Zakharchenko NS, Tarlachkov SV, Furs OV, Dyachenko OV, Buryanov YI (2016). 35S promoter methylation in kanamycin-resistant kalanchoe (Kalanchoe pinnata L.) plants expressing the antimicrobial peptide cecropin P1 transgene. Biochemistry (Mosc) 81 (9), 968–971
  9. Topolyan AP, Belyaeva MA, Bykov EE, Coodan PV, Rogozhin EA, Strizhevskaya DA, Ivanova OM, Ustinov AV, Mikhura IV, Prokhorenko IA, Korshun VA, Formanovsky AA (2016). Derivatization of Aminoglycoside Antibiotics with Tris(2,6-dimethoxyphenyl)carbenium Ion. Acta Naturae 8 (3), 128–135
  10. Topolyan AP, Strizhevskaya DA, Belyaeva MA, Brylev VA, Ustinov AV, Formanovsky AA, Korshun VA (2016). A triphenylcyclopropenylium mass tag: Synthesis and application to ultrasensitive LC/MS analysis of amines. Analyst (Lond) 141 (11), 3289–3295
  11. Andronova VL, Jasko MV, Kukhanova MK, Galegov GA, Skoblov YS, Kochetkov SN (2016). Study of antiherpetic efficiency of phosphite of acycloguanosine ableto over come the barrier of resistance to acyclovir. Acta Naturae 8 (1), 74–81
  12. Esipov RS, Abramchik YA, Fateev IV, Muravyova TI, Skoblov YS, Kostromina MA, Miroshnikov AI (2016). Preparation and study of the substrate specificity of thermophilic ribokinase from Thermus sp. 2.9. Russian Journal of Biopharmaceuticals 8 (2), 3–12
  13. Vasilenko OV, Starodumova IP, Tarlachkov SV, Dorofeeva LV, Avtukh AN, Evtushenko LI (2016). Draft genome sequence of "Rathayibacter tanaceti" strain VKM Ac-2596 isolated from Tanacetum vulgare infested by a foliar nematode. Genome Announc 4 (3),
  14. Trotsenko YA, Shmareva MN, Doronina NV, Tarlachkov SV, Mustakhimov II, Vasilenko OV (2016). Draft genome sequence of Methylophaga muralis Bur 1, a haloalkaliphilic (non-methane-utilizing) methylotroph isolated from a soda lake. Genome Announc 4 (6),
  15. Vasilenko OV, Doronina NV, Shmareva MN, Tarlachkov SV, Trotsenko YA (2016). Draft genome sequence of Methyloligella halotolerans C2T, a new halotolerant methylotroph, accumulating poly-3-hydroxybutyrate and ectoine. Genome Announc 4 (5),
  16. Skoblov AY, Vichuzhanin MV, Farzan VM, Veselova OA, Konovalova TA, Podkolzin AT, Shipulin GA, Zatsepin TS (2015). Solid- and solution-phase synthesis and application of R6G dual-labeled oligonucleotide probes. Bioorg Med Chem 23 (20), 6749–6756
  17. Agapova OY, Skoblov YS, Zykov KA, Rvacheva AV, Beilina VB, Masenko VP, Chazova IE (2015). Radioligand method of assessment of human T-lymphocytes' β-adrenoceptors activity. Russ. J. Bioorganic Chem. 41 (5), 529–535
  18. Tarakanova YN, Dmitriev AD, Massino YS, Pechelulko AA, Segal OL, Skoblov YO, Ulanova TI, Lavrov VF, Dmitriev DA (2015). Effect of pH of adsorption buffers on the number and antigen-binding activity of monoclonal antibodies immobilized on the surface of polystyrene microplates. APPL BIOCHEM MICRO+ 51 (4), 462–469
  19. Топольян АП, Стрижевская ДА, Слюндина МС, Беляева МА, Иванова ОМ, Коршун ВА, Устинов АВ, Михура ИВ, Формановский АА (2015). Дериватизация первичных аминов катионом трис(2,6-диметоксифенил)метилия для анализа методом масс-спектрометрии МАЛДИ. 12 (4), 253–258
  20. Tarlachkov SV, Dyachenko OV, Cherevatenko AM, Rudenko NV, Shevchuk TV (2014). Cloning, purification and characterization of translationally fused protein DNA methyltransferase M•HhaI-EGFP. Process Biochem 49 (12), 2170–2173
  21. Topolyan AP, Brylev VA, Ustinov AV, Formanovsky AA, Korshun VA (2014). Carbocationic mass tags for information encoding and multiplex bioanalytical applications. 25 (0), 123
  22. Dyachenko OV, Tarlachkov SV, Marinitch DV, Shevchuk TV, Buryanov YI (2014). Expression of exogenous DNA methyltransferases: Application in molecular and cell biology. Biochemistry (Mosc) 79 (2), 77–87
  23. Zeifman AA, Novikov FN, Stroylov VS, Stroganov OV, Chilov GG, Skoblov AY, Miroshnikov AI, Skoblov YS (2014). 2,3-Dihydroxy-quinoxaline induces ATPase activity of Herpes Simplex Virus thymidine kinase. FEBS Lett 588 (3), 509–511
  24. Andronova VL, Jasko MV, Kukhanova MK, Skoblov YS, Deryabin PG, Galegov GA (2014). Research of suppression of the herpes simplex virus reproduction with drug resistance by combination phosphite of acycloguanosine with some antiherpetic drugs. Vopr Virusol 59 (6), 32–35
  25. Mikoulinskaia GV, Taran SA, Skoblov YS, Feofanov SA (2013). The study of the bacteriophage T5deoxynucleoside monophosphate kinase active site by site-directed mutagenesis. Russ. J. Bioorganic Chem. 39 (6), 607–618
  26. Guskova AA, Skoblov MY, Lavrov AV, Zubtsov DA, Andronova VL, Goldshtein DV, Galegov GA, Skoblov YS (2013). Molecular genetic analysis of DNA polymerase and thymidine kinase genes of a HSV-1 population using an MPS technology. Mol Biol 47 (4), 524–529
  27. Микулинская ГВ, Таран СА, Скоблов ЮС, Феофанов СА (2013). Изучение активного центра дезоксирибонуклеозидмонофосфаткиназы бактериофага Т5 методом сайт-направленного мутагенеза. Bioorg Khim 39 (6), 1–14
  28. GusKova AA, Skoblov MY, Andronova VL, Galegov GA, Kochetkov SN, Skoblov YS (2011). Enzymatic activity of thymidine kinases of a herpes simplex virus strains resistant to acyclovir H-phosphonates. Russ. J. Bioorganic Chem. 37 (5), 560–563
  29. Stepanenko VN, Esipov RS, Miroshnikov AI, Andronova VL, Galegov GA, Yasko MV, Guskova AA, Skoblov AY, Skoblov YS (2011). Cloning, expression, isolation, and properties of Thymidine kinase from herpes simplex virus type 1, strain L2. Russ. J. Bioorganic Chem. 37 (4), 436–440
  30. Korovina AN, Guskova AA, Skoblov MY, Andronova VL, Galegov GA, Kochetkov SN, Kukhanova MK, Skoblov YS (2010). Mutations in the DNA polymerase and thymidine kinase genes of herpes simplex virus clinical isolates resistant to antiherpetic drugs. Mol Biol 44 (3), 431–438
  31. Skoblov MY, Shibanova ED, Kovaleva EV, Bairamashvili DI, Skoblov YS, Miroshnikov AI (2010). DNA Assay for Recombinant Pharmaceutical Substances Using the Real_Time PCR Technique. Russ. J. Bioorganic Chem. 36 (1), 104–108
  32. Skoblov MY, Shibanova ED, Kovaleva EV, Bairamashvilli DI, Skoblov YS, Miroshnikov AI (2010). DNA assay for recombinant pharmaceutical substances using the real-time PCR technique. Russ. J. Bioorganic Chem. 36 (1), 104–108
  33. Skoblov AY, Mikoulinskaia GV, Taran SA, Miroshnikov AI, Feofanov SA, Skoblov YS (2009). Substrate specificity of T5 bacteriophage deoxyribonucleoside monophosphate kinase and its application for the synthesis of [α-32P]d/rNTP. Russ. J. Bioorganic Chem. 35 (6), 734–738
  34. GusKova AA, Skoblov MY, Korovina AN, Yasko MV, Karpenko IL, Kukhanova MK, Andronova VL, Galegov GA, Skoblov YS (2009). Antiherpetic properties of acyclovir 5′-hydrogenphosphonate and the mutation analysis of herpes virus resistant strains. Chem Biol Drug Des 74 (4), 382–389
  35. Khandazhinskaya AL, Yanvarev DV, Jasko MV, Shipitsin AV, Khalizev VA, Shram SI, Skoblov YS, Shirokova EA, Kukhanova MK (2009). 5′-aminocarbonyl phosphonates as new zidovudine depot forms: Antiviral properties, intracellular transformations, and pharmacokinetic parameters. Drug Metab Dispos 37 (3), 494–501
  36. Скоблов АЮ, Микулинская ГВ, Таран СА, Мирошников АИ, Феофанов СА, Скоблов ЮС (2009). Субстратная специфичность дезоксирибонуклеозидмонофосфаткиназы фага Т5 и ее использование для синтеза [α-32P]d/rNTP. Bioorg Khim 35 (6), 816–821
  37. Yanvarev DV, Shirokova EA, Kukhanova MK, Skoblov YS (2008). A new chemical method of synthesis of modified nucleoside [ 32P]phosphates. J Labelled Compd 51 (8), 303–307
  38. Chekhonin VP, Bulanov KA, Yusubalieva GM, Tsibulkina EA, Gurina OI, Skoblov YS, Shvets VI, Zhirkov YA, Baklaushev VP (2008). Biodegradation of125I-labeled monoclonal antibodies after intravenous administration to rats with experimental C6 glioma. Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry 2 (1), 82–87
  39. Skoblov AY, Semenyuk AN, Murabuldaev AM, Sosunov VV, Viktorova LS, Skoblov YS (2007). Isosteric triphosphonate analogues of dNTP: Synthesis and substrate properties toward various DNA polymerases. Russ. J. Bioorganic Chem. 33 (5), 488–498
  40. Yanvarev DV, Shirokova EA, Astapova MV, Shram VI, Kukhanova MK, Skoblov YS (2007). 5′-carbamoylphosphonyl-[6-3H]-AZT as a tool for studying metabolic transformations of the nonradioactive counterpart, an inhibitor of HIV replication. Nucleosides Nucleotides Nucleic Acids 26 (89), 897–900
  41. Chekhonin VP, Bulanov KA, Yusubalieva GM, Tsibulkina EA, Gurina OI, Skoblov YS, Shvets VI, Zhirkov YA, Baklaushev VP (2007). Biodegradation of125I-labeled monoclonal antibodies after introvenous administration to rats with experimental C6 glioma. Biomed Khim 53 (5), 532–540
  42. Yanvarev DV, Shirokova EA, Astapova MV, Skoblov YS (2007). AZT 5′-cholinephosphate as an anti-HIV agent: The study of biochemical properties and metabolic transformations using its32P-labelled counterpart. Nucleosides Nucleotides Nucleic Acids 26 (1), 23–36
  43. Chuvikovsky DV, Esipov RS, Skoblov YS, Chupova LA, Muravyova TI, Miroshnikov AI, Lapinjoki S, Mikhailopulo IA (2006). Ribokinase from E. coli: Expression, purification, and substrate specificity. Bioorg Med Chem 14 (18), 6327–6332
  44. Yanvarev DV, Shirokova EA, Skoblov YS (2005). The study of coupling agents for the phosphorylation of 3′-azido-3′-deoxythymidine with [32P]orthophosphoric acid. Bioorg Khim 31 (4), 399–403
  45. Skoblov AY, Yasko MV, Murabuldaev AM, Kukhanova MK, Skoblov YS (2005). Enzymatic synthesis of bis(5′-nucleosidyl) tetra- and triphosphates. Russ. J. Bioorganic Chem. 31 (6), 563–566
  46. Yanvarev DV, Shirokova EA, Skoblov YS (2005). The study of coupling agents for phosphorylation of 3′-azido- 3′-deoxythymidine with [32P]orthophosphoric acid. Russ. J. Bioorganic Chem. 31 (4), 357–361
  47. Aleksandrov AN, Skoblov YS, Skoblov MY, Shibanova ED, Bairamashvili DI, Miroshnikov AI (2005). A PCR-based semiquantitative assay of DNA impurities in recombinant protein preparations. Russ. J. Bioorganic Chem. 31 (1), 66–69
  48. Shirokova EA, Jasko MV, Khandazhinskaya AL, Ivanov AV, Yanvarev DV, Skoblov YS, Mitkevich VA, Bocharov EV, Pronyaeva TR, Fedyuk NV, Kukhanova MK, Pokrovsky AG (2004). Uncharged AZT and D4T derivatives of phosphonoformic and phosphonoacetic acids as anti-HIV pronucleosides. J Med Chem 47 (14), 3606–3614
  49. Andronova VL, Alexandrova LA, Karpenko IL, Skoblov YS (2003). Study of 4′-thio-5-ethyl-2′-deoxyuridine and its derivatives at murine experimental infection caused by herpes simplex virus. Antibiot Med Biotekhnol 48 (5), 3–6
  50. Rozynov BV, Bogdanova IA, Shiyan SD, Shulman ML, Usubalieva LR, Khorlin AY (1976). Mass-spectrometric behavior of some C-glycopyranoside acetates. B ACAD SCI USSR CH+ 25 (5), 1126–1128
  51. Ponomarev GV, Kirillova GV, Rozynov BV, Bogdanova IA, Babushkina TA (1975). Porphyrins - III. Synthesis and properties of porphyrins with hydroxyalkyl substituents. Chem Heterocycl Compd (N Y) 11 (12), 1386–1391
  52. Rozynov BV, Sudnik MV, Shapiro AB, Sadovskaya VL, Bogdanova IA, Reshetova OS, Nekhamkina LG, Brodskii ES, Romantsev MF, Rozantsev EG (1975). Peculiarities of the mass spectrometric behavior of nitroxide biradicals with a system of σ- and σ - π-bonds. B ACAD SCI USSR CH+ 24 (4), 736–740

Скоблов Юрий Самойлович

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