Prostaglandin E1has been shown to interact with serum high density lipoproteins (HDL) in a manner resembling the interaction of a ligand with a high affinity binding site. The presence of 10-12-10-10M prostaglandin E1induces a rearrangement of the HDL surface lipids and probably influences the biological functions of the lipoproteins. Fluorescent phospholipid probe High density lipoprotein Prostaglandin E1. © 1984.