Mol Gen Genet, 1983, 190(2):344-348

RNA polymerase rifampicin resistance mutations in Escherichia coli: Sequence changes and dominance

Five recombinant plasmids, pBK2646, pBK611, pRC3, pRC4 and pRC5, carrying rpoB rifampicin-resistant RNA-polymerase genes were obtained. The sequence analysis of these plasmids revealed certain structural changes in the rpoB gene which specify corresponding alterations in the β-subunit of RNA polymerase. Some functional properties of the corresponding mutant strains and their RNA polymerases have been investigated. © 1983 Springer-Verlag.

Ovchinnikov YA, Monastyrskaya GS, Guriev SO, Kalinina NF, Sverdlov ED, Gragerov AI, Bass IA, Kiver IF, Moiseyeva EP, Igumnov VN, Mindlin SZ, Nikiforov VG, Khesin RB

IBCH: 2912
Ссылка на статью в журнале: http://link.springer.com/10.1007/BF00330662
Кол-во цитирований на 02.2024: 86
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