Angew Chem Int Ed Engl, 2015, 54(24):7065-7067

Novel Mechanism of Bioluminescence: Oxidative Decarboxylation of a Moiety Adjacent to the Light Emitter of Fridericia Luciferin

KGaA, Weinheim. Abstract A novel luciferin from a bioluminescent Siberian earthworm Fridericia heliota was recently described. In this study, the Fridericia oxyluciferin was isolated and its structure elucidated. The results provide insight into a novel bioluminescence mechanism in nature. Oxidative decarboxylation of a lysine fragment of the luciferin supplies energy for light generation, while a fluorescent CompX moiety remains intact and serves as the light emitter. Let there be light: The oxyluciferin from the bioluminescent worm Fridericia heliota was isolated and its structure elucidated. The results provide insight into a novel bioluminescence mechanism. Oxidative decarboxylation of a lysine fragment of the luciferin supplies energy for light generation, while a fluorescent CompX moiety remains intact and serves as the light emitter.

IBCH: 4016
Ссылка на статью в журнале: http://doi.wiley.com/10.1002/anie.201501668
Кол-во цитирований на 06.2020: 19
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