Russian Scientists Propose Novel Approach to Spinal Cord Injury Treatment Based on Chemokine Receptor Blockade
Scientists from the State Research Center IBCh RAS, together with leading physicians from the N.N. Burdenko Center for Neurosurgery, have discovered that the blockade of inflammation in the spinal cord, which is forced by the immune system, during the acute period of traumatic injury, has evident clinical benefits in terms of subsequent recovery. The results of cytokine profiling and magnetic resonance imaging/tractography indicate a significant improvement in the rate of neural conduction regeneration when immunoglobulin and low-molecular-weight chemokine receptor blockers are administered to injured animals. It is worth noting that some of these drugs are already actively used for the treatment of other diseases, which makes it possible to quickly translate them into clinical practice. The study results are published in the prestigious scientific journal Advanced Science. Learn more
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