IBCh authors: Mirkasymov A, Pokhorukov D, Belyaev IB, Kotelnikova P, Griaznova O, Zelepukin IV, Deyev SM
Lung Delivery of Antibiotics Using Metal-Organic Frameworks Shows Promise Against Respiratory Infections
Researchers from the Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, MEPhI, the Kurchatov Institute, and Uppsala University have developed a novel nanoparticle system for the effective delivery of rifampicin to the lungs. Using metal-organic frameworks (MOFs) with a MIL-101(Cr) structure, the team achieved high antibiotic loading and sustained release, offering a potential breakthrough in treating bacterial lung infections, including tuberculosis. The study was published in the journal Biomedical Materials. Learn more
27 января