In order to develop innovative methods of plant protection, the key properties of Tween 80aqueous micellar solutions as means of delivery of biologically active substances inhibiting thereproduction of various pathogens have been studied. The absence of negative effects of thesesolutions upon contact with potato leaves has been shown. The wetting isotherms for Tween 80aqueous solutions confirmed the hydrophilization of the potato leaf and the hydrophobic polymerfilm modeling its surface. By combining the methods of tensiometry and wetting, the maximumadsorption of Tween 80 on the surface of the polymer was determined, which made it possible topredict the structure of the adsorption layer of this surfactant on the surface of the potato leaf. Formicellar solutions of Tween 80, characterized by maximum wetting ability, a significant increasein the rate of penetration into the leaf was recorded.