IBCh authors: Parshina EA, Orlov EE, Zaraisky AG & Martynova NY
Сytoskeleton protein Zyxin inhibits retinoic acid signaling by destabilizing maternal mRNA of nuclear receptor RXRγ
In a new study, researchers from the Laboratory of molecular bases of embryogenesis, Institute of Bioorganic Chemistry, Russian Academy of Sciences, demonstrated the versatility of the previously discovered mechanism of maternal genes mRNA destabilization caused by an interaction between the cytoskeletal protein Zyxin and the mRNA-binding factor Ybx1, showing that the same mechanism governs the retinoic acid signaling pathway during early embryonic development. The work was published in the International Journal of Molecular Sciences. Learn more
may 20, 2022