Eksp i Klin Farm, 2018, 81(3):12-14

Analgesic activity of a natural peptide capable of specific binding to purinergic (P2x3) receptors

Results of investigation of the analgesic activity of the natural recombinant peptide PT1, which specifically binds to P2X3 receptors, are presented. The test for hypersensitivity provoked by complete Freund's adjuvant (CFA) showed evidence of the analgesic activity of PT1 peptide in CD-I mice after single intravenous administration in a dose range of 0.01-1 mg/kg.

Palikova YA, Zharmukhamedova TY, Palikov VA, Khokhlova ON, Osipova GA, Andreev YA, Logashina YA, Kozlov SA, Yavorskii AN, Murashev AN, DYachenko IA

Laboratory of neuroreceptors and neuroregulators, Laboratory of Biological Testing

: 10.30906/0869-2092-2018-81-3-12-14
Scopus: 2-s2.0-85048670760
IBCH: 3279
Ссылка на статью в журнале: http://ekf.folium.ru/index.php/ekf/article/view/2081
Кол-во цитирований на 08.2025: 1
Данные статьи проверены модераторами 2018-01-06