Eur J Med Chem, 2018, 141:51-60

Synthesis and biological evaluation of novel non-racemic indole-containing allocolchicinoids

Their cytotoxic properties, apoptosis-inducing activity, tubulin assembly inhibition and short-time cytotoxic effects were investigated. Compound 7 demonstrated the most pronounced anti-cancer activity: IC50

Shchegravina ES, Maleev AA, Ignatov SK, Gracheva IA, Stein A, Schmalz HG, Gavryushin AE, Zubareva AA, Svirshchevskaya EV, Fedorov AY

Laboratory of cell interactions

: 10.1016/j.ejmech.2017.09.055
Scopus: 2-s2.0-85030868814
: 29028531
IBCH: 3360
Ссылка на статью в журнале: https://linkinghub.elsevier.com/retrieve/pii/S0223523417307705
Кол-во цитирований на 06.2026: 29
Данные статьи проверены модераторами 2018-01-06