Bull Exp Biol Med, 2020, 169(3):383-387

Production of Recombinant Protein Self-Assembly Nanocontainers in a Prokaryotic System.

We optimized a method for the preparation and purification of self-assembled protein nanocontainers EPN, the latest achievement in protein engineering. These nanocontainers are highly stable and provide the possibility of highly specific loading of a protein therapeutic drug. The described technique can be proposed as a tool for production of nanocontainers in a prokaryotic system. The obtained nanocontainers for the delivery of protein preparations can be used in the treatment of chronic, autoimmune, and oncological diseases.

Ovchinnikova LA, Terekhov SS, Filimonova IN, Kudryaeva AA, Lomakin YA

Laboratory of biocatalysis, Laboratory of hormonal regulation proteins, Laboratory of bioinformatics approaches in combinatorial chemistry and biology, Laboratory of antibiotic resistance

: 10.1007/s10517-020-04892-9
Scopus: 2-s2.0-85088972867
: 32749563
IBCH: 8712
Ссылка на статью в журнале: http://link.springer.com/10.1007/s10517-020-04892-9
Нет данных о цитировании
Данные статьи проверены модераторами 2020-08-06

Список научных проектов, где отмечена публикация

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