Genome Med, 2026, 18(1):20

Inference of SARS-CoV-2 exposure biomarkers using large-scale T-cell repertoire profiling

The COVID-19 pandemic offers a powerful opportunity to develop methods for monitoring the spread of infectious diseases based on their signatures in population immunity. Adaptive immune receptor repertoire sequencing (AIRR-seq) has become the method of choice for identifying T cell receptor (TCR) biomarkers encoding pathogen specificity and immunological memory. AIRR-seq can detect imprints of past and ongoing infections and facilitate the study of individual responses to SARS-CoV-2, as shown in many recent studies.

Vlasova EK, Nekrasova AI, Komkov AY, Izraelson M, Snigir EA, Mitrofanov SI, Yudin VS, Makarov VV, Keskinov AA, Korneeva D, Pivnyuk A, Shelyakin PV, Mamedov IZ, Rebrikov DV, Yudin SM, Skvortsova VI, Chudakov DM, Britanova OV, Shugay M

IBCH: 12476
Ссылка на статью в журнале: https://link.springer.com/10.1186/s13073-025-01589-4
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Данные статьи проверены модераторами 2026-09-06

Список научных проектов, где отмечена публикация

  1. 25-75-30013. . Внебюджетное финансирование.