Guryanova Svetlana Vladimirovna has been working at the IBCh RAS since 1987, after graduating from the Biology Department, Moscow State University. In 1993, Guryanova S.V. got Ph.D. degree at the Institute of Bioorganic Chemistry, Russian Academy of Sciences, on the topic "Study of the immunomodulatory properties of synthetic bacterial glycopeptides", speciality molecular biology. Scientific activity of S.V. Guryanova is devoted to the study of the features of the functioning of the innate immunity during inflammation, pathophysiological processes, in models of allergic and neurodegenerative diseases, the definition of molecular mechanisms underlying the transmission of the signal of interaction of ligands with NLR -receptors, as well as the effect of muramil peptides and other ligands of innate immunity on the pathogenesis of significant diseases. Within the framework of government contracts, Guryanova S.V. took part in the study of the effect of nanoparticles based on WNT1-lentivirus in mouse models of cancer, as well as the effect of nanoparticles based on chitosan with B-epitopes of allergens and universal T-epitopes of the H1N1 influenza virus with the aim of developing synthetic peptide multivalent vaccines for the treatment of allergy to house dust mites and A. fumigatus. As an expert S.V. Guryanova was invited to the international systems biology project SBV Improver Challenge, and in 2014 she was recognized as the best expert along with 10 representatives from other countries. Guryanova S.V. under a contract with the Ministry of Education and Science, she organized and took part in preclinical and clinical trals of promising drugs, has extensive experience in conducting post-marketing clinical trials in compliance with all regulations.
Guryanova S.V. is the author of over 90 scientific publications, co-author of monographs: 1) Modern Approach to Systems Biology. Biological Networks and Pathway Analysis. Springer / Edited by Editors: Tatiana V. Tatarinova, Yuri Nikolsky. 2017. Publ. Humana Press Inc., Totowa, NJ, United States., 2) Potential Role for Ceramides in Neurodegenerative Diseases ./ Sphingomyelin and Ceramides: Occurrence, Biosynthesis and Role in Disease, Edited by Editors: Cecilia L. Watkins, 2015: Nova Science Publishers ., ISBN: 978-1-63482-553-5, Reports have been repeatedly noted in national and international scientific events. Guryanova S.V. is the author of two patents.
Guryanova S.V. collaborates with the laboratories of the Institute of Biochemical Chemistry of the Russian Academy of Sciences and the branch of the IBCh RAS, the Institute of Biochemical Physics named after N.M. Emanuel RAS, Institute of Biochemistry. Bach RAS, FGBU SSC Institute of Immunology, FMBA of Russia, Moscow State University named after M.V. Lomonosov, First Moscow State Medical University , RUDN University, Russian National Research Medical University, the Institute of Gerontology (St. Petersburg), Kazan State Medical University, Kuban State University, FGBOU Kuban State University of Physical Culture, Sports and Tourism, with foreign scientific, educational centers and pharmaceutical companies.