Natalia R. Onishchenko

Education

PeriodCountry, cityEducation institutionAdditional info
2002–2007 Russia Moscow State University, Department of Chemistry M.Sc., Chemistry (Thesis Title “Study of Stability of Liposomal Constructions Containing Lipophilic Derivatives of Antitumor Drugs Methotrexate and Melphalan”)
2010 Liège, Belgium University of Liège, CEIB Traineeship in frames of the Nanobiopharmaceutics project (development and characterization of polycation-based drug-delivery systems; hemocompatibility of nanoparticulate drug delivery systems)
2007–2012 Moscow, Russia M.M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences PhD student

Scientific interests

Liposomes, lipophilic prodrugs, drug delivery, nano-sized drug delivery systems' characteristics (composition, morphology, stability, cytotoxicity, interaction with biological media, hemocompatibility, biocompatibility), scientific writing.

Scientific societies’ membership

International Liposome Society

Grants & projects

PeriodAdditional info
2010–2010 The NanoBioPharmaceutics (Nanoscale Functionalities for Targeted Delivery of Biopharmaceutics) project  http://www.nanobiopharmaceutics.org/ 
2009–2010 09-04-00313-а. Fluorescence study of interactions of the antitumor agent carrying liposomes with malignant cells. 
2010–2010 10-04-01021 а. Design of targeted liposomes loaded with new antimitotic agents and studies on their antitumour effect in experimental animals.
2012–2013 12-04-31739 mol_а. Development of liposomal forms of anticancer agents methotrexate and melphalan.
2018–2015 13-04-00069. Studies on the mechanism of interaction with cells of anticancer liposomes with lipophilic prodrugs
2015–2017 15-33-20523. Novel fluorescent indicators of phospholipase A2 specificity and activity.
2015–2017 15-04-07415. Studies of lipid-protein interactions in cells and biological membranes with the help of fluorescent lipid probes
2016–2018 16-04-01585. Studies of the fate of antitumor liposomes loaded in the bilayer with lipophilic prodrug of methotrexate in human plasma
2019–1970 19-015-00499. Interactions of antitumor liposomes carrying lipophilic prodrugs in the bilayer with endothelial cells and blood plasma proteins under dynamic conditions: biomodelling in a microchannel of a microfluidic device

Selected publications (show all)

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Scientific projects

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