Pulsed laser reshaping and fragmentation of upconversion nanoparticles – from hexagonal prisms to 1D nanorods through “Medusa”-like structures
Researchers from the Federal Research Center "Crystallography and Photonics" and the Institute of Bioorganic Chemistry RAS, together with colleagues from Austria, Germany and France, have developed a technology for 1D-nanostructure fabrication. One-dimensional upconversion nanocrystals (UCNPs) with unique optical properties and morphology have been prepared by the laser-induced recrystallization of nanostate. Exposure to picosecond laser irradiation of UCNPs with a core/shell structure (β-Na1.5Y1.5F6:Yb3+, Tm3+/β-Na1.5Y1.5F6) led to a controlled dynamic nanotransformation of luminescent 3D-structure into 1D with inherent optical properties through the formation of particles with unusual “medusa”-like architecture. The proposed technology based on picosecond laser treatment enables UCNP surface hydrophilization and performs the transformation from "nano" to "nano", which ensures the preparation of nanoagents for biovisualization and therapy. The research was published in the journal Nano Research.
- Genomic DNA i-motifs as fast sensors responsive to near-physiological pH microchanges
Researchers from Federal Research and Clinical Center of Physical-Chemical medicine and Institute of Bioorganic Chemistry RAS, in collaboration with Skolkovo University of Science and Technology and D.Mendeleev University of Chemical Technology of Russia developed simple and robust sensors for detecting microchanges in intracellular pH.
- From cytoskeleton to pluripotency: a new mechanism for regulating stem status of the embryonic cells
Researchers from the Laboratory of Molecular Bases of Embryogenesis (Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS), in technical cooperation with colleagues from the Department of Metabolism and Redox Biology (Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS), the Laboratory of Genomics and Epigenomics of Vertebrates in the Federal Center "Fundamentals of Biotechnology" RAS, as well as with colleagues from the Cell Motility Group of the Institute of Protein Research RAS, discovered a previously unknown mechanism of the regulation of the activity of genes that determine the pluripotent status of the embryonic stem cells.
- Dual Targeting of Cancer Cells with DARPin-Based Toxins for Overcoming Tumor Escape
Researchers of the Laboratory of Molecular Immunology, IBCh RAS, in collaboration with Russian colleagues have shown that the strategy of targeting of anticancer toxins to two different surface antigens on the surface of a cancer cell is effective in the treatment of not only primary solid tumors, but also distant metastases.
- International School "Molecular mechanisms of neurodegenerative diseases"
XI.26.20 (This event is over)
Moscow Institute of Physics and Technology (MIPT) invites you to take part in the International school for young scientists "Molecular mechanisms of neurodegenerative diseases", which will be held on November 26, 2020 online.
- Lipids 2021 Conference
Lipids 2021 Conference, October 19-21, 2021, IBCH RAS, Moscow
- Lecture by Director-General of the ICGEB Lawrence Banks «Human Papillomaviruses: From Infectious Entry to Malignancy»
I.27.20 (This event is over)
ICGEB Director-General Group Leader Lawrence Banks will deliver a lecture entitled «Human Papillomaviruses: From Infectious Entry to Malignancy». Date and time: Mon 27 January 2020 14:00. Location: Small conference hall at 3rd floor BON IBCh.