From 2003 on the base of the Institutes Experimental biotechnology plant there is producing of the first Russian recombinant human insulin Insuran R and Insuran NPH. For this development, scientists of the IBCh RAS with their leader academician Anatoly Miroshnikov received RF Government Prize in the field of science and technology in 2006.
- Liquid but Durable: Molecular Dynamics Explains Unique Character of Archaeal Biomembranes
Archaea, initially known as archaebacteria, mostly are extremophiles: they thrive environments of high temperature, pressure, salinity and acidity. Probably, “special path” of archaea was predestined by unique properties of their membranes, which significantly differ from bacterial and eukaryotic ones. In Laboratory of biomolecular modeling at IBCh, Russian Academy of Sciences, a computational study was conducted to discover relationship between chemical structure of archaeal lipids and physical properties of the membranes. The work was published in Scientific Reports.
- Ganglioside GD2 as a Key Tool Towards Novel Anti-Cancer Therapy
Besides proteins, glycosphingolipids and in particularly ganglioside GD2 can be treated as targets for anti-cancer therapy. It has been discovered that classic immune antitumor mechanisms are not exclusive (and probably are not the main) reasons of therapeutic activity of GD2-specific antibodies. In the study, carried out in the Group of molecular modulators of immunity in IBCh RAS, at the first time was proved unique property of ganglioside GD2 to activate “suicide” of tumor cells after it binding with GD2-specific antibodies. The project aimed to develop new anticancer drugs based on this study recently has received approval by the Skolkovo Foundation.
- Nadya Pletneva won the L'Oréal-UNESCO Award for Women in Science
Our congratulations to Nadya and her coworkers on this remarkable achievement! The award aims to improve the position of women in science by recognizing outstanding women researchers.
- Microscale Thermophoresis (MST) allows quantification of binding affinities of proteins, nucleic acids and small molecules as well as measurement of enzymatic activities.
XII.15–17 (This event is over)
December 17th, 2014, 10.00, IBCH RAS, Seminar room korp.33, floor 1 (NMR lab.)
- 7th Russian-Japanese Symposium “Molecular Simulation Studies in Material and Biological Sciences”
IX.21–22 (This event is over)
MSSMBS symposium is held in IBCh on September 22, 2014 (BON, 5th floor).
- International Conference on Laboratory animal science
IV.7 VI.1 (This event is over)
Rus-LASA and ICLAS joint Conference "Science-bases assessment of laboratory animal welfare" 17-19 November 2014, S. Petersburg, Russia