Researchers from the Laboratory of Molecular Bases of Embryogenesis (Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS), in technical cooperation with colleagues from the Department of Metabolism and Redox Biology (Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS), the Laboratory of Genomics and Epigenomics of Vertebrates in the Federal Center "Fundamentals of Biotechnology" RAS, as well as with colleagues from the Cell Motility Group of the Institute of Protein Research RAS, discovered a previously unknown mechanism of the regulation of the activity of genes that determine the pluripotent status of the embryonic stem cells.

Researchers of the Laboratory of Molecular Immunology, IBCh RAS, in collaboration with Russian colleagues have shown that the strategy of targeting of anticancer toxins to two different surface antigens on the surface of a cancer cell is effective in the treatment of not only primary solid tumors, but also distant metastases.

Unlike the tightly controlled replication of DNA in living cells, PCR amplification, a “workhorse” of molecular biology, balances between simplicity and accuracy. Conventional “bulk” PCR often yields inefficient and nonuniform amplification of complex templates in DNA libraries, introducing unwanted biases.

Lipids 2021 Conference, October 19-21, 2021, IBCH RAS, Moscow