Sculpture of valinomycin in complex with potassium ion reminds us about fundamental meaning of depsipeptides

In 1982 in front of the IBCh RAS was placed sculpture of valinomycin in complex with potassium ion which reminds us about fundamental meaning of depsipeptides, structure and action mechanism of which were examined in detail by scientists of IBCh under the direction of Yuri Ovchinnikov.


  • The way to study of tyrosine kinases receptor science news IV.23

    Receptor tyrosine kinases - one of the key links in a cell signaling system. They play a key role in the regulation of intercellular interactions, cell proliferation, morphogenesis and metabolism. Their dysfunctions are associated with such socially significant diseases as cancer and diabetes. In M.M. Shemyakin and Yu.A. Ovchinnikov Institute of bioorganic chemistry several research groups perform researches, concerning receptor tyrosine kinases.

  • Discovered а new signaling mechanism of brain development regulation science news IV.23

    A new signaling mechanism regulating brain development was discovered by group of scientists from Laboratory of molecular bases of embryogenesis of M.M. Shemyakin and Yu. A. Ovchinnikov Institute of bioorganic chemistry. The article about it was published in Biology Open journal.

  • Model of receptor actication IRR science news IV.14

    The group of the researchers from Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry together with the student from Moscow Institute of Physics and Technology studied structural features of the receptor IRR (IRR - Insulin receptor-related receptor) and proposed a model of its activation, which has been described in detail in an article published in Biochimie.