-Разработка и создание системы направленной доставки белковых препаратов для терапии аутоиммунных и онкологических заболеваний на основе внеклеточных везикул

January 6, 2022 — December 31, 2024

Lomakin Y.A. (PI)

Laboratory of biocatalysis

Grant, RSF

List of publications

  1. Ovchinnikova LA, Zalevsky AO, Lomakin YA (2022). Extracellular Vesicles in Chronic Demyelinating Diseases: Prospects in Treatment and Diagnosis of Autoimmune Neurological Disorders. Life (Basel) 12 (11),
  2. Ovchinnikova LA, Dzhelad SS, Simaniv TO, Zakharova MN, Lomakin YA, Gabibov AG, Illarioshkin SN (2024). Development of a Panel of Biomarkers for Differential Diagnosis of Multiple Sclerosis. Dokl Biochem Biophys 519 (1), 593–596
  3. Ishina IA, Zhiyanov AP, Kurbatskaya IN, Mamedov AE, Nersisyan , Ziganshin RH, Eliseev IE, Petrusenko YS, Nikonova AV, Zhbanova ES, Salnikova MA, Ovchinnikova LA, Mamedov IZ, Davydov AN, Nurbaeva KS, Lisitsyna TA, Reshetnyak TM, Lila AM, Nasonov EL, Lomakin YA, Belogurov AA, Zhang H, Tonevitskiy AG, Rubtsov YP, Gabibov AG, Zakharova MY (2024). Autoantigenic peptide landscape of rheumatoid arthritis-associated HLA class II. Genes Dis 12 (4), 101469
  4. Ovchinnikova LA, Eliseev IE, Dzhelad SS, Simaniv TO, Klimina KM, Ivanova M, Ilina EN, Zakharova MN, Illarioshkin SN, Rubtsov YP, Gabibov AG, Lomakin YA (2024). High heterogeneity of cross-reactive immunoglobulins in multiple sclerosis presumes combining of B-cell epitopes for diagnostics: a case-control study. Front Immunol 15, 1401156
  5. Ovchinnikova LA, Tanygina DY, Dzhelad SS, Evtushenko EG, Bagrov DV, Gabibov AG, Lomakin YA (2024). Targeted macrophage mannose receptor (CD206)-specific protein delivery via engineered extracellular vesicles. Heliyon 10 (24), e40940
  6. Ovchinnikova LA, Lomakin YA (2025). Extracellular Vesicles As a Source of Biomarkers for Cancer Diagnosis. Acta Naturae 17 (2), 28–40