Institute of
bioorganic chemistry

A study by an international team of scientists led by researchers from the Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences (IBCh RAS) has been published in Nature Plants. The study presents and validates a simple and elegant approach to making autonomous bioluminescent reporters resistant to metabolic fluctuations. The researchers developed pairs of luciferases that use the same substrate but emit light of different colors and demonstrated that the ratio between the two signals reflects reporter gene activity rather than the metabolic state of the cell. This approach enables long- term monitoring of plant hormone signaling and defense responses. Learn more