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Mechanism of coelenterazine chromophore photoinactivation from Beroe abissycola photoprotein is proposed

Scientists from IBCh RAS with colleagues from Photobiology Lab (IBP SB RAS) elucidated the structures of Beroe abissycola photoprotein’s chromophore photoinactivation products and proposed a mechanism of the photoinactivation process. The similarity of chemical transformations of photoprotein and GFP-like fluorescent protein chromophores was demonstrated for the first time. The results are published in Organic Letters. The project was funded by the RScF grant № 17-14-01169p.

 

photoproteins, bioluminescence

Grigorov A.S.

august 27, 2021