MENDELEEV COMMUN, 2023, 33(4):476-478

Synthesis of disaccharides for the study of human blood antibodies capable of recognizing the inner Glcβ1-3GalNAc disaccharide fragment of bacterial polysaccharides

Disaccharides with the terminal Glcβ1-3 motif were synthesized as probes for studying human blood antibodies. An antibody isolated using Glcβ1-3GalNAcα–Sepharose was found to bind the inner part of the polysaccharide [–4GlcA6LThr3Acβ1-6Galβ1-6Glcβ1-3GalNAc6Acβ1–]n as evidenced by the use of a printed glycan array and inhibition assays.

Pazynina GV, Tsygankova SV, Obukhova PS, Shilova NV, Paramonov AS, Chizhov AO, Knirel YA, Bovin NV

Laboratory of structural biology of ion channels, Department of Chemical Biology of Glycans and Lipids, Laboratory of Carbohydrates

: 10.1016/j.mencom.2023.06.011
Scopus: 2-s2.0-85166556673
IBCH: 10860
Ссылка на статью в журнале: https://linkinghub.elsevier.com/retrieve/pii/S0959943623001827
Кол-во цитирований на 02.2026: 1
Данные статьи проверены модераторами 2023-09-19

Список научных проектов, где отмечена публикация

  1. -Естественные антигликановые антитела с цитотоксическим действием (January 6, 2022 — December 31, 2023). Shilova N.V.. Grant, RSF.