Chem Heterocycl Compd (N Y), 2024, 60(9/10):544-548

The cycloaddition reaction of benzothiazolium ylides with α-cyanocinnamamides: the synthesis of structural analogs of inhibitors of HIV-1 post-integrational repair

Benzothiazolium ylides generated in situ from benzothiazolium salts by the action of triethylamine reacted stereoselectively with α-cyanocinnamamides to form 1,2,3,3a-tetrahydropyrrolo[2,1-b][1,3]benzothiazoles in 15–91% yields. The resulting compounds were significantly more stable than their analogs derived from quinolinium ylides (KuINin), inhibitors of HIV-1 post-integrational repair.

Molchanova MV, Ikonnikova VA, Anisenko AN, Gottikh MB, Baranov MS, Mikhaylov AA

Laboratory of chemistry of heterocyclic compounds, Group of chemistry of natural products

: 10.1007/s10593-024-03373-5
Scopus: 2-s2.0-85213733142
IBCH: 11717
Ссылка на статью в журнале: https://link.springer.com/article/10.1007/s10593-024-03373-5
Кол-во цитирований на 05.2026: 3
Данные статьи проверены модераторами 2025-01-16

Список научных проектов, где отмечена публикация

  1. Arylidene-azol-ones in the synthesis of spirocyclic compounds: new approaches, substrates and catalysts. (August 14, 2023 — June 30, 2026). Mikhaylov A.A., Myasnyanko I.N., Smirnov A.Y., Sokolov A.I., Ikonnikova V.A.. Grant, RSF.