Arylidene-azol-ones in the synthesis of spirocyclic compounds: new approaches, substrates and catalysts.

August 14, 2023 — June 30, 2026

Mikhaylov A.A. (PI), Myasnyanko I.N. (Co-PI), Smirnov A.Y. (Co-PI), Sokolov A.I. (Co-PI), Ikonnikova V.A.

Laboratory of chemistry of heterocyclic compounds, Group of chemistry of natural products

Grant, RSF

List of publications

  1. Ivanov DS, Smirnov AY, Zaitseva ER, Mikhaylov AA, Baranov MS (2023). Synthesis of Densely Substituted Pyridines via 1,2-Oxazine-6-ones Inverse Electron Demand Diels-Alder Reaction. European J Org Chem 27 (1),
  2. Molchanova MV, Ikonnikova VA, Smirnov AY, Solyev PN, Baranov MS, Mikhaylov AA (2024). Synthesis of Spiro[imidazole-4,3′-pyrrolo[1,2-a]quinolin]- 5-ones via 1,3-Dipolar Cycloaddition of Quinolinium Ylides with Arylydeneimidazol-4-ones. ChemistrySelect 9 (8), e202305123
  3. Krasnova SA, Zaitseva ER, Rudik DI, Ivanov DS, Mikhaylov AA, Baranov MS (2024). Arylidene-Imidazolones and Their Acyclic Analogue as Fluorescent Sensors of Metal Ions. Russ. J. Bioorganic Chem. 50 (2), 617–624
  4. Tiushina IV, Sokolov AI, Smirnov AY, Dubinnyi MA, Ivanov DS, Korlyukov AA, Mikhaylov AA, Baranov MS (2024). [3+2] Cycloaddition of N-benzylazomethine Methylide with Various Arylidene-Azolones. ChemistrySelect 9 (18),
  5. Molchanova MV, Ikonnikova VA, Anisenko AN, Gottikh MB, Baranov MS, Mikhaylov AA (2024). The cycloaddition reaction of benzothiazolium ylides with α-cyanocinnamamides: the synthesis of structural analogs of inhibitors of HIV-1 post-integrational repair. Chem Heterocycl Compd (N Y) 60 (9/10), 544–548
  6. Al Mufti AM, Ikonnikova VA, Smirnov AC, Solyev PN, Korlyukov AA, Azmi MN, Baranov MS, Mikhaylov AA (2025). Tracking the reactivity of arylideneimidazol-4-ones in the Diels–Alder cycloaddition. MENDELEEV COMMUN 35 (5), 512–514
  7. Rudik DI, Smirnov AY, Eshtukov-Shcheglov AV, Baranov MS (2025). Synthesis of 3-Carbamoylpyrazol-5-ylphosphonates from Arylmethylideneimidazolones. RUSS J ORG CHEM+ 61 (9), 1609–1614
  8. Rudik DI, Tiushina IV, Sokolov AI, Smirnov AY, Romanenko AR, Korlyukov AA, Mikhaylov AA, Baranov MS (2025). [3 + 2] Cycloaddition of thioformylium methylide with various arylidene-azolones in the synthesis of 7-thia-3-azaspiro[4.4]nonan-4-ones. Beilstein J Org Chem 21 (1), 1791–1798
  9. Gilvanov AR, Molchanova MV, Krasnova SA, Eshtukov-Shcheglov AV, Mikhaylov AA, Goncharuk SA, Goncharuk MV, Sidorenko SV, Maksimov EG, Baranov MS, Bogdanova YA (2025). Bathochromic Shift via C=O to C=S Substitution: A Far-Red Fluorogen for Multiplexed FLIM with FAST Fluorogen-Activating Protein. Int J Mol Sci 27 (1), 23
  10. Ikonnikova VA, Shchigal OE, Anisenko AN, Solyev PN, Krylkov GA, Romanenko AR, Korlyukov AA, Baranov MS, Gottikh MB, Mikhaylov AA (2026). Cycloaddition of benzo[d]thiazoles with imidazol-4-one-activated donor–acceptor cyclopropanes: synthesis of spirocyclic inhibitors of HIV-1. Org Biomol Chem 24 (15), 3232–3238
  11. Krasnova SA, Mikhaylov AA, Baranov MS (2026). Synthesis and Study of the Optical Properties of a New Green Fluorescent Protein Chromophore Analogue with an sp-Hybridized Carbon Fragment. Russ. J. Bioorganic Chem. 52 (1), 23
  12. Opryshko VE, Smirnov AY, Bogdanova YA, Mikhaylov AA, Krasnova SA, Rudik DI, Romanenko AR, Korlyukov AA, Baranov MS, Ivanov DS (2026). Cycloaddition of 2-mercaptobenzaldehyde with 5-arylidene-2-thioxooxazolidin-4-ones. MENDELEEV COMMUN 36 (4), 457–459
  13. Al Mufti AM, Kungurtsev KD, Kashapov AI, Korlyukov AA, Romanenko AA, Solyev PN, Ikonnikova VA, Azmi MN, Baranov MS, Mikhaylov AA (2026). (3+3)-Cycloaddition-Based Synthesis of Spirocyclic 1,2-Oxazinanes Fused With Imidazol-4-One. ChemistrySelect 11 (30),