MENDELEEV COMMUN, 2026, 36(4):457-459

Cycloaddition of 2-mercaptobenzaldehyde with 5-arylidene-2-thioxooxazolidin-4-ones

A simple diastereoselective synthesis of 4'-hydroxy-2-thioxospiro[oxazolidine-5,3'-thiochroman]-4-ones comprises the [4 + 2] cycloaddition of 2-mercaptobenzaldehyde with 5-arylidene-3-phenyl-2-thioxooxazolidin-4-ones. In case of DABCO as the base, (2'R*,4'R*,5S*)-diastereomers predominate while L-proline is responsible for (2'R*,4'S*,5S*)-configuration of the products.

Opryshko VE, Smirnov AY, Bogdanova YA, Mikhaylov AA, Krasnova SA, Rudik DI, Romanenko AR, Korlyukov AA, Baranov MS, Ivanov DS

Laboratory of chemistry of heterocyclic compounds, Group of chemistry of natural products

: 10.71267/mencom.7959
Scopus: 2-s2.0-105041559454
IBCH: 12642
Ссылка на статью в журнале: https://www.mathnet.ru/mendc7462
Кол-во цитирований на 06.2026: 0
Данные статьи проверены модераторами 2026-09-27

Список научных проектов, где отмечена публикация

  1. Arylidene-azol-ones in the synthesis of spirocyclic compounds: new approaches, substrates and catalysts. (August 14, 2023 — June 30, 2026). Mikhaylov A.A., Myasnyanko I.N., Smirnov A.Y., Sokolov A.I., Ikonnikova V.A.. Grant, RSF.