Adaptive immune response of identical twins to live vaccine
T-cell receptors (TCRs) play a key role in adaptive immunity. TCR repertoire is very diverse and unique to each individual because it forms in the stochastic DNA recombination process. The group of scientists from the Department of genomics of adaptive immunity in collaboration with ENS (Paris, France) studied TCR repertoires of identical twins after immunization with a live vaccine. In each donor, they identified about a thousand different T-cell clones responding to immunization. Responding clones have almost unique repertoire in each donor with higher overlap in identical twin pairs. The study was supported by RSF and published in Proceedings of the National Academy of Sciences.
- Nobel Prize winner, Arieh Warshel took part in the meeting of the IBCh RAS scientific council and joined the international advisory Board of the Institute
April 3rd 2019, a regular meeting of the IBCh RAS Scientific Council took place, featuring the 2013 Chemistry Nobel Prize awardee, Arieh Warshel. The scientist delivered a short talk, regarding the prospects of contemporary science and possibilities of using the quantum mechanics calculations to predict the behavior of complex systems, up to the organs and organisms. Director of our Institute, Alexander Gabibov, announced that professor Warshel had joined the International Advisory Board of the Institute, along with several other distinguished scientists, and presented him a symbolical gift.
- Scientists present a fully genetically encodable bioluminescent system
Scientists from Russia, UK, Spain, Brazil, Japan, and Austria discovered the essential set of enzymes that allows glowing fungi to emit light. The bioluminescent system includes a brand- new luciferase and three enzymes that enable biosynthesis of fungal luciferin from a widespread metabolite – caffeic acid – as well as its recycling. The genes encoding this “caffeic acid cycle” make up a unique molecular toolkit that allows to turn any higher organism into a glowing one. The work was published in Proceedings of the National Academy of Sciences of the United States of America.
- Kurt Wüthrich took part in the workshop of the Structural biology department
Professor Kurt Wüthrich, Nobel Laureate in Chemistry, 2002, visited Shemyakin–Ovchinnikov Institute of bioorganic chemistry RAS and took part in the workshop of the Structural biology department of the Institute (headed by Prof. Alexander Arseniev).
- 12th INTERNATIONAL CONFERENCE “BIOCATALYSIS.FUNDAMENTALS & APPLICATIONS” “BIOCATALYSIS-2019”
Dear colleagues, The Lomonosov Moscow State University and RAS institutes, including IBCH RAS, is planning to convene a traditional biannual 12 th International Conference "BIOCATALYSIS-2019" in June, 24–28, 2019. Conference will be convened on board a ship cruising via the route St. Petersburg – Valaam – Kizhi – St. Petersburg. More info is available at http://bc2019.org/.
- "Molecular Brain" seminar
IV.16 (This event is over)
The seminar is timed to the birthday of academician Eugene Grishin and will take place on April 16 at 14:00 in the Hall of Academic Council. Members of the Department of Molecular Neurobiology created by Eugene, will give talks on their present work. Everyone is cordially invited.
- Microscopic Imaging of Epigenetic Landscape - A Universal Platform to Study Epigenetic Changes at Single Cell Level
II.15 (This event is over)