• Kurt Wüthrich took part in the workshop of the Structural biology department science news X.10

    Professor Kurt Wüthrich, Nobel Laureate in Chemistry, 2002, visited Shemyakin–Ovchinnikov Institute of bioorganic chemistry RAS and took part in the workshop of the Structural biology department of the Institute (headed by Prof. Alexander Arseniev).

  • Ras-dva: make regeneration great again science news IX.17

    The researchers from Laboratory of molecular bases of embryogenesis recently hypothesised that the decrease of limb regeneration capacity in amniotes (reptiles, birds and mammals) could be caused by elimination in evolution of genes, encoding for important regulators of specific wound epithelium and blastema organization, which are used by excellent regenerating anamniotes (fish and amphibia). Using two anamniotic model organisms Danio rerio adult fishes and Xenopus laevis tadpoles the authors have shown the essential role of Ras-dva small GTPases in regulation of these processes, meanwhile their genes are eliminated in a stepwise manner during evolution till total absence in placental mammals. The obtained results support the hypothesis. The investigation is published in Scientific reports.

  • A bright bantam: BrUSLEE – green fluorescent protein with the unique properties science news IX.7

    Researchers from the Biophotonics lab of IBCH RAS (Anastasia Mamontova, Konstantin Lukyanov and Alexey Bogdanov) designed a new green fluorescent protein that combines high fluorescence brightness and short fluorescence lifetime. They used a semi-rational protein evolution approach. Their collaborators from Bach Institute of Biochemistry and Semenov Institute of Physical Chemistry helped with the time-resolved fluorescence analysis (FLIM) that allowed characterizing the physical properties of this perspective probe. Research has recently been published in the Scientific Reports.