
Dual Targeting of Cancer Cells with DARPin-Based Toxins for Overcoming Tumor Escape
Researchers of the Laboratory of Molecular Immunology, IBCh RAS, in collaboration with Russian colleagues have shown that the strategy of targeting of anticancer toxins to two different surface antigens on the surface of a cancer cell is effective in the treatment of not only primary solid tumors, but also distant metastases. The proposed approach can serve as a potential therapeutic strategy that surpasses mono-specific targeting strategies in the anti-cancer efficacy. Results of the research are published in Cancers. Learn more
News 
- Genomic DNA i-motifs as fast sensors responsive to near-physiological pH microchanges
science news
I.4 Researchers from Federal Research and Clinical Center of Physical-Chemical medicine and Institute of Bioorganic Chemistry RAS, in collaboration with Skolkovo University of Science and Technology and D.Mendeleev University of Chemical Technology of Russia developed simple and robust sensors for detecting microchanges in intracellular pH.
- From cytoskeleton to pluripotency: a new mechanism for regulating stem status of the embryonic cells
science news
XI.17.20 Researchers from the Laboratory of Molecular Bases of Embryogenesis (Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS), in technical cooperation with colleagues from the Department of Metabolism and Redox Biology (Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS), the Laboratory of Genomics and Epigenomics of Vertebrates in the Federal Center "Fundamentals of Biotechnology" RAS, as well as with colleagues from the Cell Motility Group of the Institute of Protein Research RAS, discovered a previously unknown mechanism of the regulation of the activity of genes that determine the pluripotent status of the embryonic stem cells.
- Dual Targeting of Cancer Cells with DARPin-Based Toxins for Overcoming Tumor Escape
science news
XI.17.20 Researchers of the Laboratory of Molecular Immunology, IBCh RAS, in collaboration with Russian colleagues have shown that the strategy of targeting of anticancer toxins to two different surface antigens on the surface of a cancer cell is effective in the treatment of not only primary solid tumors, but also distant metastases.
Events 
- International School "Molecular mechanisms of neurodegenerative diseases"
conferences
XI.26.20 (This event is over) Moscow Institute of Physics and Technology (MIPT) invites you to take part in the International school for young scientists "Molecular mechanisms of neurodegenerative diseases", which will be held on November 26, 2020 online.
- Lipids 2021 Conference
conferences
X.19–21 Lipids 2021 Conference, October 19-21, 2021, IBCH RAS, Moscow
- Lecture by Director-General of the ICGEB Lawrence Banks «Human Papillomaviruses: From Infectious Entry to Malignancy»
science news
I.27.20 (This event is over) ICGEB Director-General Group Leader Lawrence Banks will deliver a lecture entitled «Human Papillomaviruses: From Infectious Entry to Malignancy». Date and time: Mon 27 January 2020 14:00. Location: Small conference hall at 3rd floor BON IBCh.