Bioorg Med Chem Lett, 2017, 27(11):2484-2487
New modified 2-aminobenzimidazole nucleosides: Synthesis and evaluation of their activity against herpes simplex virus type 1
2-Amino-5,6-difluoro-benzimidazole riboside proved to exhibit a selective antiviral activity (selectivity index 32) against a wild strain of the herpes simplex virus type 1, as well as towards virus strains that are resistant to acyclovir, cidofovir, and foscarnet. We believe that this compound might be used for treatment of herpes infections in those cases, when acyclovir is not efficient.
Scopus: 2-s2.0-85017403447
: 28408228
IBCH: 4054
Ссылка на статью в журнале: https://linkinghub.elsevier.com/retrieve/pii/S0960894X17303633
Кол-во цитирований на 04.2024: 15
Данные статьи проверены модераторами 2017-01-06