Nucleosides Nucleotides, 1997, 16(3):215-225
Synthesis and DNA duplex stabilities of oligonucleotides containing C- 5-(3-methoxypropynyl)-2'-deoxyuridine residues
5'-Dimethoxytrityl-5-(3-methoxypropynyl)-2'-deoxyuridine phosphoroamidite was synthesized with the use of commercial 3- methoxypropyne. Oligonucleotides (ODNs) containing 5-(3-methoxypropynyl)-2'- deoxyuridine in different positions were prepared. The stabilities of the duplexes formed by these ODNs with the complementary templates are increased in comparison with the unmodified counterparts. On average modified residue incorporated, the Tm is raised by 1°C.
Scopus: 2-s2.0-0031003520
IBCH: 6201
Ссылка на статью в журнале: https://www.tandfonline.com/doi/full/10.1080/07328319708001343
Кол-во цитирований на 01.2024: 4
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