Org Biomol Chem, 2006, 4(6):1091-1096
5-Arylethynyl-2′-deoxyuridines, compounds active against HSV-1
Three new 5-arylethynyl-2′-deoxyuridines containing bulky aryls have been prepared and tested against HSV-1 in Vero cells. The introduction of a substituent in the phenyl group of an inactive compound, 5-phenylethynyl- 2′-deoxyuridine, leads to the appearance of anti-HSV properties. The most active compounds are those containing a polycyclic aromatic hydrocarbon residue attached to the 5 position of 2′-deoxyuridine through a rigid triple bond. © The Royal Society of Chemistry 2006.
Scopus: 2-s2.0-33644899418
: 16525553
IBCH: 980
Ссылка на статью в журнале: http://xlink.rsc.org/?DOI=b516804j
Кол-во цитирований на 11.2023: 28
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