Dmitry B. Staroverov


Research fellow (Group of Structural Organization of T-cell Immunity)

Phone: +7 (499) 742-81-22

E-mail: dstaroverov@evrogen.ru

Selected publications

  1. Egorov ES, Kasatskaya SA, Zubov VN, Izraelson M, Nakonechnaya TO, Staroverov DB, Angius A, Cucca F, Mamedov IZ, Rosati E, Franke A, Shugay M, Pogorelyy MV, Chudakov DM, Britanova OV (2018). The changing landscape of naive T cell receptor repertoire with human aging. Front Immunol 9 (0), 1618
  2. Sycheva AL, Pogorelyy MV, Komech EA, Minervina AA, Zvyagin IV, Staroverov DB, Chudakov DM, Lebedev YB, Mamedov IZ (2018). Quantitative profiling reveals minor changes of T cell receptor repertoire in response to subunit inactivated influenza vaccine. Vaccine 36 (12), 1599–1605
  3. Markina NM, Pereverzev AP, Staroverov DB, Lukyanov KA, Gurskaya NG (2018). Generation of cell lines stably expressing a fluorescent reporter of nonsense-mediated mRNA decay activity. Methods Mol Biol 1720 (0), 187–204
  4. Ermakova YG, Pak VV, Bogdanova YA, Kotlobay AA, Yampolsky IV, Shokhina AG, Panova AS, Marygin RA, Staroverov DB, Bilan DS, Sies H, Belousov VV (2018). SypHer3s: A genetically encoded fluorescent ratiometric probe with enhanced brightness and an improved dynamic range. Chem Commun (Camb) 54 (23), 2898–2901
  5. Izraelson M, Nakonechnaya TO, Moltedo B, Egorov ES, Kasatskaya SA, Putintseva EV, Mamedov IZ, Staroverov DB, Shemiakina II, Zakharova MY, Davydov AN, Bolotin DA, Shugay M, Chudakov DM, Rudensky AY, Britanova OV (2017). Comparative analysis of murine T-cell receptor repertoires. Immunology 153 (2), 133–144
  6. Merzlyak EM, Kasatskaya SA, Sosnovskaya AV, Israelson MA, Staroverov DB, Nakonechnaya TO, Novikov PI, Chudakov DM, Britanova OV (2017). Long-term effect of high cyclophosphamide doses on the repertoire of T-cell receptors of peripheral blood T-lymphocytes in patients with autoimmune vasculitis. Bulletin of Russian State Medical University 6 (5), 68–74
  7. Ermakova YG, Lanin AA, Fedotov IV, Roshchin M, Kelmanson IV, Kulik D, Bogdanova YA, Shokhina AG, Bilan DS, Staroverov DB, Balaban PM, Fedotov AB, Sidorov-Biryukov DA, Nikitin ES, Zheltikov AM, Belousov VV (2017). Thermogenetic neurostimulation with single-cell resolution. Nat Commun 8 (0), 15362
  8. Turchaninova MA, Davydov A, Britanova OV, Shugay M, Bikos V, Egorov ES, Kirgizova VI, Merzlyak EM, Staroverov DB, Bolotin DA, Mamedov IZ, Izraelson M, Logacheva MD, Kladova O, Plevova K, Pospisilova S, Chudakov DM (2016). High-quality full-length immunoglobulin profiling with unique molecular barcoding. Nat Protoc 11 (9), 1599–1616
  9. Ryumina AP, Serebrovskaya EO, Staroverov DB, Zlobovskaya OA, Shcheglov AS, Lukyanov SA, Lukyanov KA (2016). Lysosome-associated minisog as a photosensitizer for Mammalian cells. Biotechniques 61 (2), 92–94
  10. Britanova OV, Shugay M, Merzlyak EM, Staroverov DB, Putintseva EV, Turchaninova MA, Mamedov IZ, Pogorelyy MV, Bolotin DA, Izraelson M, Davydov AN, Egorov ES, Kasatskaya SA, Rebrikov DV, Lukyanov S, Chudakov DM (2016). Dynamics of individual T Cell repertoires: From cord blood to centenarians. J Immunol 196 (12), 5005–5013
  11. Gurskaya NG, Pereverzev AP, Staroverov DB, Markina NM, Lukyanov KA (2016). Analysis of Nonsense-Mediated mRNA Decay at the Single-Cell Level Using Two Fluorescent Proteins. Methods Enzymol 572 (0), 291–314
  12. Gurskaya NG, Staroverov DB, Lukyanov KA (2016). Fluorescent Protein-Based Quantification of Alternative Splicing of a Target Cassette Exon in Mammalian Cells. Methods Enzymol 572 (0), 255–268
  13. Sarkisyan KS, Zlobovskaya OA, Gorbachev DA, Bozhanova NG, Sharonov GV, Staroverov DB, Egorov ES, Ryabova AV, Solntsev KM, Mishin AS, Lukyanov KA (2015). KillerOrange, a genetically encoded photosensitizer activated by blue and green light. PLoS One 10 (12), e0145287
  14. Pereverzev AP, Matlashov ME, Staroverov DB, Lukyanov KA, Gurskaya NG (2015). Differences in nonsense-mediated mRNA decay activity in mammalian cell lines revealed by a fluorescence reporter. Russ. J. Bioorganic Chem. 41 (5), 525–528
  15. Egorov ES, Merzlyak EM, Shelenkov AA, Britanova OV, Sharonov GV, Staroverov DB, Bolotin DA, Davydov AN, Barsova E, Lebedev YB, Shugay M, Chudakov DM (2015). Quantitative profiling of immune repertoires for minor lymphocyte counts using unique molecular identifiers. J Immunol 194 (12), 6155–6163
  16. Zvyagin IV, Pogorelyy MV, Ivanova ME, Komech EA, Shugay M, Bolotin DA, Shelenkov AA, Kurnosov AA, Staroverov DB, Chudakov DM, Lebedev YB, Mamedov IZ (2014). Distinctive properties of identical twins' TCR repertoires revealed by high-throughput sequencing. Proc Natl Acad Sci U S A 111 (16), 5980–5985
  17. Britanova OV, Putintseva EV, Shugay M, Merzlyak EM, Turchaninova MA, Staroverov DB, Bolotin DA, Lukyanov S, Bogdanova EA, Mamedov IZ, Lebedev YB, Chudakov DM (2014). Age-Related decrease in TCR repertoire diversity measured with deep and normalized sequence profiling. J Immunol 192 (6), 2689–2698
  18. Shugay M, Britanova OV, Merzlyak EM, Turchaninova MA, Mamedov IZ, Tuganbaev TR, Bolotin DA, Staroverov DB, Putintseva EV, Plevova K, Linnemann C, Shagin D, Pospisilova S, Lukyanov S, Schumacher TN, Chudakov DM (2014). Towards error-free profiling of immune repertoires. Nat Methods 11 (6), 653–655
  19. Putintseva EV, Britanova OV, Staroverov DB, Merzlyak EM, Turchaninova MA, Shugay M, Bolotin DA, Pogorelyy MV, Mamedov IZ, Bobrynina V, Maschan M, Lebedev YB, Chudakov DM (2013). Mother and child T cell receptor repertoires: Deep profiling study. Front Immunol 4 (0), 463
  20. Turchaninova MA, Britanova OV, Bolotin DA, Shugay M, Putintseva EV, Staroverov DB, Sharonov G, Shcherbo D, Zvyagin IV, Mamedov IZ, Linnemann C, Schumacher TN, Chudakov DM (2013). Pairing of T-cell receptor chains via emulsion PCR. Eur J Immunol 43 (9), 2507–2515
  21. Shemiakina II, Ermakova GV, Cranfill PJ, Baird MA, Evans RA, Souslova EA, Staroverov DB, Gorokhovatsky AY, Putintseva EV, Gorodnicheva TV, Chepurnykh TV, Strukova L, Lukyanov S, Zaraisky AG, Davidson MW, Chudakov DM, Shcherbo D (2012). A monomeric red fluorescent protein with low cytotoxicity. Nat Commun 3 (0), 1204
  22. Britanova OV, Bochkova AG, Staroverov DB, Fedorenko DA, Bolotin DA, Mamedov IZ, Turchaninova MA, Putintseva EV, Kotlobay AA, Lukyanov S, Novik AA, Lebedev YB, Chudakov DM (2012). First autologous hematopoietic SCT for ankylosing spondylitis: A case report and clues to understanding the therapy. Bone Marrow Transplant 47 (11), 1479–1481
  23. Gurskaya NG, Staroverov DB, Zhang L, Fradkov AF, Markina NM, Pereverzev AP, Lukyanov KA (2012). Analysis of alternative splicing of cassette exons at single-cell level using two fluorescent proteins. Nucleic Acids Res 40 (8), e57
  24. Britanova OV, Staroverov DB, Chkalina AV, Kotlobay AA, Zvezdova ES, Bochkova AG, Chudakov DM (2011). Single high-dose treatment with glucosaminyl-muramyl dipeptide is ineffective in treating ankylosing spondylitis. Rheumatol Int 31 (8), 1101–1103
  25. Gurskaya NG, Staroverov DB, Fradkov AF, Lukyanov KA (2011). The coding region of far-red fluorescent protein Katushka contains a strong donor splice site. Russ. J. Bioorganic Chem. 37 (3), 380–382
  26. Mamedov IZ, Britanova OV, Bolotin DA, Chkalina AV, Staroverov DB, Zvyagin IV, Kotlobay AA, Turchaninova MA, Fedorenko DA, Novik AA, Sharonov GV, Lukyanov S, Chudakov DM, Lebedev YB (2011). Quantitative tracking of T cell clones after haematopoietic stem cell transplantation. EMBO Mol Med 3 (4), 201–207
  27. Zvyagin IV, Mamedov IZ, Britanova OV, Staroverov DB, Nasonov EL, Bochkova AG, Chkalina AV, Kotlobay AA, Korostin DO, Rebrikov DV, Lukyanov S, Lebedev YB, Chudakov DM (2010). Contribution of functional KIR3DL1 to ankylosing spondylitis. Cell Mol Immunol 7 (6), 471–476
  28. Zvyagin IV, Dorodnykh VY, Mamedov IZ, Staroverov DB, Bochkova AG, Rebrikov DV, Lebedev YB (2010). Association of ERAP1 Allelic Variants with Risk of Ankylosing Spondylitis. Acta Naturae 2 (3), 72–7
  29. Chkalina AV, Zviagin IV, Mamedov IZ, Britanova OV, Staroverov DB, Lebedev IB (2010). The oligoclonal expansion of T cells: study of its stability over time. Bioorg Khim 36 (2), 206–214
  30. Chkalina AV, Zvyagin IV, Mamedov IZ, Britanova OV, Staroverov DB, Lebedev YB (2010). The oligoclonal expansion of T cells: The investigation of its stability over time. Russ. J. Bioorganic Chem. 36 (2), 191–198
  31. Markvicheva KN, Bogdanova EA, Staroverov DB, Lukyanov S, Belousov VV (2009). Imaging of intracellular hydrogen peroxide production with HyPer upon stimulation of HeLa cells with epidermal growth factor. Methods Mol Biol 476 (0), 76–83
  32. Mamedov IZ, Britanova OV, Chkalina AV, Staroverov DB, Amosova AL, Mishin AS, Kurnikova MA, Zvyagin IV, Mutovina ZY, Gordeev AV, Khaidukov SV, Sharonov GV, Shagin DA, Chudakov DM, Lebedev YB (2009). Individual characterization of stably expanded T cell clones in ankylosing spondylitis patients. Autoimmunity 42 (6), 525–536
  33. Markvicheva KN, Bogdanova EA, Staroverov DB, Lukyanov S, Belousov VV (2008). Imaging of intracellular hydrogen peroxide production with hyper upon stimulation of hela cells with egf. Methods Mol Biol 476 (0), 79–86
  34. Anisimova VE, Rebrikov DV, Shagin DA, Kozhemyako VB, Menzorova NI, Staroverov DB, Ziganshin R, Vagner LL, Rasskazov VA, Lukyanov SA, Shcheglov AS (2008). Isolation, characterization and molecular cloning of Duplex-Specific Nuclease from the hepatopancreas of the Kamchatka crab. BMC Biochem 9 (1), 14
  35. Zhang L, Gurskaya NG, Merzlyak EM, Staroverov DB, Mudrik NN, Samarkina ON, Vinokurov LM, Lukyanov S, Lukyanov KA (2007). Method for real-time monitoring of protein degradation at the single cell level. Biotechniques 42 (4), 446–450
  36. Efimov VA, Birikh KR, Staroverov DB, Lukyanov SA, Tereshina MB, Zaraisky AG, Chakhmakhcheva OG (2006). Hydroxyproline-based DNA mimics provide an efficient gene silencing in vitro and in vivo. Nucleic Acids Res 34 (8), 2247–2257
  37. Anisimova VE, Rebrikov DV, Zhulidov PA, Staroverov DB, Lukyanov SA, Shcheglov AS (2006). Renaturation, activation, and practical use of recombinant duplex-specific nuclease from Kamchatka crab. Biochemistry (Mosc) 71 (5), 513–519
  38. Gurskaya NG, Verkhusha VV, Shcheglov AS, Staroverov DB, Chepurnykh TV, Fradkov AF, Lukyanov S, Lukyanov KA (2006). Engineering of a monomeric green-to-red photoactivatable fluorescent protein induced by blue light. Nat Biotechnol 24 (4), 461–465
  39. Belousov VV, Fradkov AF, Lukyanov KA, Staroverov DB, Shakhbazov KS, Terskikh AV, Lukyanov S (2006). Genetically encoded fluorescent indicator for intracellular hydrogen peroxide. Nat Methods 3 (4), 281–286
  40. Bulina ME, Chudakov DM, Britanova OV, Yanushevich YG, Staroverov DB, Chepurnykh TV, Merzlyak EM, Shkrob MA, Lukyanov S, Lukyanov KA (2006). A genetically encoded photosensitizer. Nat Biotechnol 24 (1), 95–99
  41. Chudakov DM, Verkhusha VV, Staroverov DB, Souslova EA, Lukyanov S, Lukyanov KA (2004). Photoswitchable cyan fluorescent protein for protein tracking. Nat Biotechnol 22 (11), 1435–1439
  42. Bulina ME, Lukyanov KA, Yampolsky IV, Chudakov DM, Staroverov DB, Shcheglov AS, Gurskaya NG, Lukyanov S (2004). New class of blue animal pigments based on Frizzled and Kringle protein domains. J Biol Chem 279 (42), 43367–43370
  43. Baranova A, Ivanov D, Petrash N, Pestova A, Skoblov M, Kelmanson I, Shagin D, Nazarenko S, Geraymovych E, Litvin O, Tiunova A, Born TL, Usman N, Staroverov D, Lukyanov S, Panchin Y (2004). The mammalian pannexin family is homologous to the invertebrate innexin gap junction proteins. Genomics 83 (4), 706–716
  44. Gurskaya NG, Fradkov AF, Pounkova NI, Staroverov DB, Bulina ME, Yanushevich YG, Labas YA, Lukyanov S, Lukyanov KA (2003). A colourless green fluorescent protein homologue from the non-fluorescent hydromedusa Aequorea coerulescens and its fluorescent mutants. Biochem J 373 (2), 403–408
  45. Ianushevich IG, Gurskaia NG, Staroverov DB, Lukianov SA, Lukianov KA (2003). A natural fluorescent protein that changes its fluorescence during maturation. Bioorg Khim 29 (4), 356–360
  46. Bulina ME, Verkhusha VV, Staroverov DB, Chudakov DM, Lukyanov KA (2003). Hetero-oligomeric tagging diminishes non-specific aggregation of target proteins fused with Anthozoa fluorescent proteins. Biochem J 371 (1), 109–114
  47. Chudakov DM, Belousov VV, Zaraisky AG, Novoselov VV, Staroverov DB, Zorov DB, Lukyanov S, Lukyanov KA (2003). Kindling fluorescent proteins for precise in vivo photolabeling. Nat Biotechnol 21 (2), 191–194
  48. Shagin DA, Rebrikov DV, Kozhemyako VB, Altshuler IM, Shcheglov AS, Zhulidov PA, Bogdanova EA, Staroverov DB, Rasskazov VA, Lukyanov S (2002). A novel method for SNP detection using a new duplex-specific nuclease from crab hepatopancreas. Genome Res 12 (12), 1935–1942
  49. Fradkov AF, Verkhusha VV, Staroverov DB, Bulina ME, Yanushevich YG, Martynov VI, Lukyanov S, Lukyanov KA (2002). Far-red fluorescent tag for protein labelling. Biochem J 368 (1), 17–21
  50. Yanushevich YG, Staroverov DB, Savitsky AP, Fradkov AF, Gurskaya NG, Bulina ME, Lukyanov KA, Lukyanov SA (2002). A strategy for the generation of non-aggregating mutants of Anthozoa fluorescent proteins. FEBS Lett 511 (13), 11–14