Laboratory of Plant Biotechnology

NamePositionContacts
Yaroslav Buryanov, D.Sc, professordepart. dir.buryanov@bibch.ru+7(4967)73-09-21#3228
Natalia Zakharchenko, Ph.D.s. r. f.zachar@bibch.ru
Elena Rukavtsova, D.Scs. r. f.ruk@bibch.ru+7(27)330970
Anna Lebedeva, Ph.D.s. r. f.aanlebedeva@mail.ru
Taras Shevchuk, D.Scs. r. f.shevchuk@bibch.ru
Olga Dyachenko, Ph.D.r. f.ovdyachenko@bibch.ru
Valeriya Alekseeva, Ph.D.r. f.lera@bibch.ru
Svetlana Pigoleva, Ph.D.r. f.svoil@rambler.ru

Former members:

Sergey Tarlachkoveng.sergey@tarlachkov.ru

Selected publications (show all)

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Yaroslav Buryanov

  • Russia, Moscow, Ul. Miklukho-Maklaya 16/10 — On the map
  • IBCh RAS, build. ФИБХ, office. Переход/439
  • Phone: +7(4967)73-09-21#3228
  • E-mail: buryanov@bibch.ru

Resistance of bombinin-expressing plants to phytopathogens (2018-11-26)

Transgenic plants expressing artificial gene of an antimicrobial peptide bombinin have been produced and investigated. This plants were resistant to the Erwinia carotovora bacteria and Rhizoctonia solani fungi phytopathogens. Such plants expressing the small antimicrobial peptide gene are promising for new approach in plant protection agriculture technology.

Biological activity of water extract of cecropin P1-expressing Kalanchoe plants (2017-11-27)

Water extract of constructed Kalanchoe pinnata plants expressing antimicrobial peptide cecropin P1 (cecP1) has been analyzed in the experiments on plants and animals. The extract has effectively induced rhizogenesis on callus culture of Mesembryanthemum crystallinum plants, difficult object for differentiation in vitro. High wound healing (Fig. 1) and and microbiocide activity of the cecP1-plant extract, better than efficiency of Cefazolin antibiotic against Staphylococcus aureus and Pseudomonas aeruginosa, causative agents of purulent infections (Fig. 2), and efficiency of Clotrimazolum antifungal drug against highly virulenr clinical isolate Candida albicans were found. These data demonstrate good prospects for use cecP1-kalanchoe plants in experimental biology and pharmaceutics.

Obtaining of plants with increased expression of HBsAg as edible vaccine against hepatitis B (2016-03-18)

The new expression system created for increased synthesis of proteins in plants under the control of promoter 35S RNA of cauliflower mosaic virus (CaMV 35S) containing four enhancer sequences CaMV 35S and nontranslated leader sequence Ω RNA of tobacco mosaic virus. The immunogenicity of HBsAg synthesized by potato tubers was shown in experiments on mice. Increased synthesis of target proteins allows the use of transgenic plants as edible vaccine against the hepatitis B without additional injections of recombinant vaccine.