The unit was disbanded in 2018.

Laboratory of proteomics

Department of Peptide and Protein Technologies

Head: Vadim Govorun, member of the academy of sciences
govorun@hotmail.ru+7(495)336-07-77

proteome, peptidome, mass-spectrometry

NamePositionContacts
Vadim Govorun, member of the academy of sciencesdepart. dir.govorun@hotmail.ru+7(495)336-07-77
Sergej Grachjov, Ph.D.s. r. f.+7(495)330-61-65
Rustam Ziganshin, Ph.D.s. r. f.rustam.ziganshin@gmail.com+7(495)995-55-57#2101
Vasilij Kadykov, D.Scs. r. f.vakad@ibch.ru+7(495)336-19-88
Dmitrij Klinov, Ph.D.s. r. f.klinov@ibch.ru+7(495)336-19-88
Anna Seredina, Ph.D.j. r. f.
Olga IvanovaPhD stud.ivolga-msu@mail.ru
Nikolay AnikanovPhD stud.koenzyme@mail.ru
Regina KhazigaleevaPhD stud.ajregi_12@mail.ru+7(916)1717582
Elena PushkovaPhD stud.
Irina GagarinaPhD stud.irinagaranina24@gmail.com
Victor Demin, Ph.D.eng.vvdem@ibch.ru+7(495)336-19-88
Nataliya Logvina, Ph.D.eng.logvina@genebee.msu.ru
Igor' Azarkinres. eng.garik.igor.azar@gmail.com+7(495)336-07-77

Former members:

Yury Kozmins. r. f.zibotic@mail.ru
Konstantin Mochalov, Ph.D.r. f.mochalov@mail.ru
Ekaterina Obraztsovar. f.e.a.obraztsova@gmail.com
Igor Fesenko, Ph.D.r. f.argus220@mail.ru
Andrey Knyazev, Ph.D.r. f.agrofak@gmail.com
Anna Mamaevar. f.
Sergej Kovalchuk, Ph.D.j. r. f.xerx222@gmail.com
Regina Azarkinaj. r. f.
Viktoria ShenderPhD stud.shender_vika@mail.ru
Galina Petrovat. q. - lab. as.
Veronika Manohinares. eng.
Aleksej Mezinres. eng.

Selected publications (show all)

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Vadim Govorun

Alternative splicing shapes transcriptome but not proteome diversity in Physcomitrella patens (2017-12-05)

Alternative splicing (AS) can significantly impact the transcriptome and proteome of a eukaryotic cell. We analyzed the extent to which AS contributes to proteome diversity using moss Physcomitrella patens as a model object. We could distinguish a few examples that unambiguously indicated the presence of two or more splice isoforms from the same locus at the proteomic level. Our results indicate that alternative isoforms have a small effect on proteome diversity. We also revealed that mRNAs and pre-mRNAs have thousands of complementary binding sites for long non-coding RNAs (lncRNAs) that may lead to potential interactions in transcriptome. This finding points to an additional level of gene expression and AS regulation by non-coding transcripts in Physcomitrella patens.

Publications

  1. Fesenko I, Khazigaleeva R, Kirov I, Kniazev A, Glushenko O, Babalyan K, Arapidi G, Shashkova T, Butenko I, Zgoda V, Anufrieva K, Seredina A, Filippova A, Govorun V (2017). Alternative splicing shapes transcriptome but not proteome diversity in Physcomitrella patens. Sci Rep 7 (1), 2698