MENDELEEV COMMUN, 2021, 31(4):490-492

Synthesis of spacer armed Kdn(2→6') and (2→3')-lactosamines for immunochemical research

Glycosylation of lactosamine acceptors with Kdn thioglycoside donors in the presence of NIS/TfOH as a promoter affords products with both α- and β-ketosidic linkage (2–6' or 2–3') between the Kdn and Gal residues. After deprotection, the synthesized trisaccharides and glycans containing Neu5Ac were printed to a chip and their comparative interaction with human serum antibodies was explored.

Chinarev AA, Sablina MA, Kunetskiy RA, Shilova NV, Polyakova SV, Paramonov AS, Saha J, Bovin NV

Department of structural biology, Laboratory of structural biology of ion channels, Department of Chemical Biology of Glycans and Lipids, Laboratory of Carbohydrates

: 10.1016/j.mencom.2021.07.017
Scopus: 2-s2.0-85113693630
IBCH: 9508
Ссылка на статью в журнале: https://linkinghub.elsevier.com/retrieve/pii/S0959943621001917
Кол-во цитирований на 11.2023: 3
Данные статьи проверены модераторами 2021-10-24

Список научных проектов, где отмечена публикация

  1. - (January 6, 2018 — December 31, 2022). Bovin N.V.. Grant, RFBR.