Полянский Антон Александрович

Образование

Период обученияСтрана, городУчебное заведениеДополнительная информация
1998–2003 Москва Биологический факультет МГУ красный диплом

Избранные публикации

  1. Polyansky AA, Bocharov EV, Velghe AI, Kuznetsov AS, Bocharova OV, Urban AS, Arseniev AS, Zagrovic B, Demoulin JB, Efremov RG (2019). Atomistic mechanism of the constitutive activation of PDGFRA via its transmembrane domain. BIOCHIM BIOPHYS ACTA 1863 (1), 82–95
  2. Zagrovic B, Bartonek L, Polyansky AA (2018). RNA-protein interactions in an unstructured context. FEBS Lett 592 (17), 2901–2916
  3. Bocharov EV, Bragin PE, Pavlov KV, Bocharova OV, Mineev KS, Polyansky AA, Volynsky PE, Efremov RG, Arseniev AS (2017). The Conformation of the Epidermal Growth Factor Receptor Transmembrane Domain Dimer Dynamically Adapts to the Local Membrane Environment. Biochemistry 56 (12), 1697–1705
  4. Kuznetsov AS, Polyansky AA, Fleck M, Volynsky PE, Efremov RG (2015). Adaptable Lipid Matrix Promotes Protein-Protein Association in Membranes. J Chem Theory Comput 11 (9), 4415–4426
  5. Zhang L, Polyansky A, Buck M (2015). Modeling transmembrane domain dimers/trimers of plexin receptors: Implications for mechanisms of signal transmission across the membrane. PLoS One 10 (4), e0121513
  6. Kuznetsov AS, Polyansky AA, Volynsky PE, Efremov RG (2015). Lipid environment promotes dimerization of transmembrane helices.  (0), 139–150
  7. Ribeiro EDA, Pinotsis N, Ghisleni A, Salmazo A, Konarev PV, Kostan J, Sjöblom B, Schreiner C, Polyansky AA, Gkougkoulia EA, Holt MR, Aachmann FL, Žagrović B, Bordignon E, Pirker KF, Svergun DI, Gautel M, Djinović-Carugo K (2014). The structure and regulation of human muscle α-Actinin. Cell 159 (6), 1447–1460
  8. Velghe AI, Van Cauwenberghe S, Polyansky AA, Chand D, Montano-Almendras CP, Charni S, Hallberg B, Essaghir A, Demoulin JB (2014). PDGFRA alterations in cancer: Characterization of a gain-of-function V536E transmembrane mutant as well as loss-of-function and passenger mutations. Oncogene 33 (20), 2568–2576
  9. Polyansky AA, Chugunov AO, Volynsky PE, Krylov NA, Nolde DE, Efremov RG (2014). PREDDIMER: A web server for prediction of transmembrane helical dimers. Bioinformatics 30 (6), 889–890
  10. Peter B, Polyansky AA, Fanucchi S, Dirr HW (2014). A lys-trp cation-π interaction mediates the dimerization and function of the chloride intracellular channel protein 1 transmembrane domain. Biochemistry 53 (1), 57–67
  11. Chugunov AO, Koromyslova AD, Berkut AA, Peigneur S, Tytgat J, Polyansky AA, Pentkovsky VM, Vassilevski AA, Grishin EV, Efremov RG (2013). Modular organization of α-toxins from scorpion venom mirrors domain structure of their targets, sodium channels. J Biol Chem 288 (26), 19014–19027
  12. Volynsky PE, Polyansky AA, Fakhrutdinova GN, Bocharov EV, Efremov RG (2013). Role of dimerization efficiency of transmembrane domains in activation of fibroblast growth factor receptor 3. J Am Chem Soc 135 (22), 8105–8108
  13. Chugunov A, Pyrkova D, Nolde D, Polyansky A, Pentkovsky V, Efremov R (2013). Lipid-II forms potential "landing terrain" for lantibiotics in simulated bacterial membrane. Sci Rep 3 (0), 1678
  14. Чугунов АО, Нольде ДЕ, Пыркова ДВ, Полянский АА, Пентковский ВМ, Ефремов РГ (2013). На пути к новым антибиотикам. 12 (0), 34–36
  15. Чугунов АО, Полянский АА, Ефремов РГ (2013). Физическая водобоязнь. 1 (0), 24–34
  16. Polyansky AA, Chugunov AO, Vassilevski AA, Grishin EV, Efremov RG (2012). Recent advances in computational modeling of α-Helical membrane-active peptides. Curr Protein Pept Sci 13 (7), 644–657
  17. Polyansky AA, Kuzmanic A, Hlevnjak M, Zagrovic B (2012). On the contribution of linear correlations to quasi-harmonic conformational entropy in proteins. J Chem Theory Comput 8 (10), 3820–3829
  18. Polyansky AA, Volynsky PE, Efremov RG (2012). Multistate organization of transmembrane helical protein dimers governed by the host membrane. J Am Chem Soc 134 (35), 14390–14400
  19. Muhle-Goll C, Hoffmann S, Afonin S, Grage SL, Polyansky AA, Windisch D, Zeitler M, Bürck J, Ulrich AS (2012). Hydrophobic matching controls the tilt and stability of the dimeric platelet-derived growth factor receptor (PDGFR) α transmembrane segment. J Biol Chem 287 (31), 26178–26186
  20. Polyansky AA, Zagrovic B (2012). Protein electrostatic properties predefining the level of surface hydrophobicity change upon phosphorylation. J Phys Chem Lett 3 (8), 973–976
  21. Polyansky AA, Zubac R, Zagrovic B (2012). Estimation of conformational entropy in protein-ligand interactions: A computational perspective. Methods Mol Biol 819 (0), 327–353
  22. Чугунов АО, Полянский АА, Ефремов РГ (2012). Липидный фундамент жизни.  (3), 3–12
  23. Kordyukova LV, Serebryakova MV, Polyansky AA, Kropotkina EA, Alexeevski AV, Veit M, Efremov RG, Filippova IY, Baratova LA (2011). Linker and/or transmembrane regions of influenza A/Group-1, A/Group-2, and type B virus hemagglutinins are packed differently within trimers. BIOCHIM BIOPHYS ACTA 1808 (7), 1843–1854
  24. Polyansky AA, Volynsky PE, Efremov RG (2011). Structural, dynamic, and functional aspects of helix association in membranes: A computational view. Adv Protein Chem Struct Biol 83 (0), 129–161
  25. Polyansky AA, Ramaswamy R, Volynsky PE, Sbalzarini IF, Marrink SJ, Efremov RG (2010). Antimicrobial peptides induce growth of phosphatidylglycerol domains in a model bacterial membrane. J Phys Chem Lett 1 (20), 3108–3111
  26. Polyansky AA, Vassilevski AA, Volynsky PE, Vorontsova OV, Samsonova OV, Egorova NS, Krylov NA, Feofanov AV, Arseniev AS, Grishin EV, Efremov RG (2009). N-terminal amphipathic helix as a trigger of hemolytic activity in antimicrobial peptides: A case study in latarcins. FEBS Lett 583 (14), 2425–2428
  27. Polyansky AA, Volynsky PE, Arseniev AS, Efremov RG (2009). Adaptation of a membrane-active peptide to heterogeneous environment. II. The role of mosaic nature of the membrane surface. J Phys Chem B 113 (4), 1120–1126
  28. Polyansky AA, Volynsky PE, Arseniev AS, Efremov RG (2009). Adaptation of a membrane-active peptide to heterogeneous environment. I. Structural plasticity of the peptide. J Phys Chem B 113 (4), 1107–1119
  29. Dubovskii PV, Volynsky PE, Polyansky AA, Karpunin DV, Chupin VV, Efremov RG, Arseniev AS (2008). Three-dimensional structure/hydrophobicity of latarcins specifies their mode of membrane activity. Biochemistry 47 (11), 3525–3533
  30. Polyansky AA, Volynsky PE, Efremov RG (2007). Computer simulations of membrane-lytic peptides: perspectives in drug design. J Bioinform Comput Biol 5 (2), 611–626
  31. Dubovskii PV, Volynsky PE, Polyansky AA, Chupin VV, Efremov RG, Arseniev AS (2006). Spatial structure and activity mechanism of a novel spider antimicrobial peptide. Biochemistry 45 (35), 10759–10767
  32. Volynsky PE, Polyansky AA, Simakov NA, Arseniev AS, Efremov RG (2005). Effect of lipid composition on the "membrane response" induced by a fusion peptide. Biochemistry 44 (44), 14626–14637
  33. Polyansky AA, Volynsky PE, Nolde DE, Arseniev AS, Efremov RG (2005). Role of lipid charge in organization of water/lipid bilayer interface: Insights via computer simulations. J Phys Chem B 109 (31), 15052–15059
  34. Polyansky AA, Kosinsky YA, Efremov RG (2004). Correlation of local changes in the temperature-dependent conformational flexibility of thioredoxins with their thermostability. Russ. J. Bioorganic Chem. 30 (5), 421–430