Anton A. Polyansky
Ph.D. (physico-mathematical sciences)
Senior research fellow (Laboratory of biomolecular modeling)
|Period||Country, city||Education institution||Additional info|
|1998–2003||Russia, Moscow||Dept. of Biophysics, Faculty of Biological Sciences M.V. Lomonosov State University||with honor|
My major interests are: 1) organization of biomolecular surfaces, 2) principles of polypeptide chain folding in different environments (water, water-lipid interface, membrane etc.), 3) mechanisms of protein oligomerization in the membrane medium, 4) protein-membrane and protein-RNA interactions, and 5) design of novel drugs, which have specific membrane targets.
In my research I use combined molecular modeling approaches. Among them are:
- coarse-grained and atomistic computer simulations of proteins, peptides and drugs in explicit solvents and membrane systems (molecular dynamics, free energy estimation etc.);
- molecular hydrophobicity potential calculations and surface analysis of biomolecules;
- bioinformatics analysis of protein and RNA sequences.