Овчинникова Татьяна Владимировна

Избранные публикации

  1. Sychev SV, Sukhanov SV, Panteleev PV, Shenkarev ZO, Ovchinnikova TV (2018). Marine antimicrobial peptide arenicin adopts a monomeric twisted β-hairpin structure and forms low conductivity pores in zwitterionic lipid bilayers. Biospectroscopy 110 (2),
  2. Kuzmin DV, Emelianova AA, Kalashnikova MB, Panteleev PV, Balandin SV, Serebrovskaya EO, Belogurova-Ovchinnikova OY, Ovchinnikova TV (2017). Comparative in vitro study on cytotoxicity of recombinant β-hairpin peptides. Chem Biol Drug Des 91 (1), 294–303
  3. Shenkarev ZO, Melnikova DN, Finkina EI, Sukhanov SV, Boldyrev IA, Gizatullina AK, Mineev KS, Arseniev AS, Ovchinnikova TV (2017). Ligand Binding Properties of the Lentil Lipid Transfer Protein: Molecular Insight into the Possible Mechanism of Lipid Uptake. Biochemistry 56 (12), 1785–1796
  4. Panteleev PV, Myshkin MY, Shenkarev ZO, Ovchinnikova TV (2017). Dimerization of the antimicrobial peptide arenicin plays a key role in the cytotoxicity but not in the antibacterial activity. Biochem Biophys Res Commun 482 (4), 1320–1326
  5. Panteleev PV, Balandin SV, Ivanov VT, Ovchinnikova TV (2017). A therapeutic potential of animal β-hairpin Antimicrobial Peptides. Curr Med Chem 24 (17), 1724–1746
  6. Finkina EI, Melnikova DN, Bogdanov IV, Ovchinnikova TV (2017). Plant pathogenesis-related proteins PR-10 and PR-14 as components of innate immunity system and ubiquitous allergens. Curr Med Chem 24 (17), 1772–1787
  7. Finkina EI, Melnikova DN, Bogdanov IV, Ovchinnikova TV (2016). Lipid Transfer Proteins As Components of the Plant Innate Immune System: Structure, Functions, and Applications. Acta Naturae 8 (2), 47–61
  8. Bogdanov IV, Shenkarev ZO, Finkina EI, Melnikova DN, Rumynskiy EI, Arseniev AS, Ovchinnikova TV (2016). A novel lipid transfer protein from the pea Pisum sativum: Isolation, recombinant expression, solution structure, antifungal activity, lipid binding, and allergenic roperties. BMC Plant Biol 16 (1), 107
  9. Sychev SV, Sukhanov SV, Telezhinskaya IN, Ovchinnikova TV (2016). Effective lipid-detergent system for study of membrane active peptides in fluid liposomes. J Pept Sci 22 (2), 98–105
  10. Shamova OV, Orlov DS, Zharkova MS, Balandin SV, Yamschikova EV, Knappe D, Hoffmann R, Kokryakov VN, Ovchinnikova TV (2016). Minibactenecins ChBac7.Nα and ChBac7. Nβ - Antimicrobial Peptides from leukocytes of the goat capra hircus. Acta Naturae 8 (3), 136–146
  11. Berlov MN, Umnyakova ES, Leonova TS, Milman BL, Krasnodembskaya AD, Ovchinnikova TV, Kokryakov VN (2015). Interaction of Arenicin-1 with C1q Protein. Bioorg Khim 41 (6), 664–668
  12. Bogdanov IV, Finkina EI, Balandin SV, Melnikova DN, Stukacheva EA, Ovchinnikova TV (2015). Structural and Functional Characterization of Recombinant Isoforms of the Lentil Lipid Transfer Protein. Acta Naturae 7 (3), 65–73
  13. Panteleev PV, Bolosov IA, Balandin SV, Ovchinnikova TV (2015). Structure and Biological Functions of β-Hairpin Antimicrobial Peptides. Acta Naturae 7 (1), 37–47
  14. Panteleev PV, Bolosov IA, Balandin SV, Ovchinnikova TV (2015). Design of antimicrobial peptide arenicin analogs with improved therapeutic indices. J Pept Sci 21 (2), 105–113
  15. Panteleev PV, Bolosov IA, Balandin SV, Ovchinnikova TV (2015). Structure and biological functions of β-hairpin antimicrobial peptides. Acta Naturae 7 (1), 37–47
  16. Bogdanov IV, Finkina EI, Balandin SV, Melnikova DN, Stukacheva EA, Ovchinnikova TV (2015). Structural and functional characterization of recombinant isoforms of the lentil lipid transfer protein. Acta Naturae 7 (3), 65–73
  17. Shamova OV, Orlov DS, Balandin SV, Shramova EI, Tsvetkova EV, Panteleev PV, Leonova YF, Tagaev AA, Kokryakov VN, Ovchinnikova TV (2014). Acipensins - Novel Antimicrobial Peptides from Leukocytes of the Russian Sturgeon Acipenser gueldenstaedtii. Acta Naturae 6 (4), 99–109
  18. Shenkarev ZO, Gizatullina AK, Finkina EI, Alekseeva EA, Balandin SV, Mineev KS, Arseniev AS, Ovchinnikova TV (2014). Heterologous expression and solution structure of defensin from lentil Lens culinaris. Biochem Biophys Res Commun 451 (2), 252–257
  19. Shenkarev ZO, Lyukmanova EN, Paramonov AS, Panteleev PV, Balandin SV, Shulepko MA, Mineev KS, Ovchinnikova TV, Kirpichnikov MP, Arseniev AS (2014). Lipid-protein nanodiscs offer new perspectives for structural and functional studies of water-soluble membrane-active peptides. Acta Naturae 6 (2), 84–94
  20. Shenkarev ZO, Lyukmanova EN, Paramonov AS, Panteleev PV, Balandin SV, Shulepko MA, Mineev KS, Ovchinnikova TV, Kirpichnikov MP, Arseniev AS (2014). Lipid-protein nanodiscs offer new perspectives for structural and functional studies of water-soluble membrane-active peptides. Acta Naturae 6 (21), 84–94
  21. Shamova OV, Orlov DS, Balandin SV, Shramova EI, Tsvetkova EV, Panteleev PV, Leonova YF, Tagaev AA, Kokryakov VN, Ovchinnikova TV (2014). Acipensins - novel antimicrobial peptides from leukocytes of the Russian sturgeon Acipenser gueldenstaedtii. Acta Naturae 6 (23), 99–109
  22. Gizatullina AK, Finkina EI, Mineev KS, Melnikova DN, Bogdanov IV, Telezhinskaya IN, Balandin SV, Shenkarev ZO, Arseniev AS, Ovchinnikova TV (2013). Recombinant production and solution structure of lipid transfer protein from lentil Lens culinaris. Biochem Biophys Res Commun 439 (4), 427–432
  23. Shenkarev ZO, Panteleev PV, Balandin SV, Gizatullina AK, Altukhov DA, Finkina EI, Kokryakov VN, Arseniev AS, Ovchinnikova TV (2012). Recombinant expression and solution structure of antimicrobial peptide aurelin from jellyfish Aurelia aurita. Biochem Biophys Res Commun 429 (12), 63–69
  24. Akkerdaas J, Finkina EI, Balandin SV, Santos Magadán S, Knulst A, Fernandez-Rivas M, Asero R, Van Ree R, Ovchinnikova TV (2011). Lentil (Lens culinaris) lipid transfer protein Len c 3: A novel legume allergen. Int Arch Allergy Immunol 157 (1), 51–57
  25. Shenkarev ZO, Balandin SV, Trunov KI, Paramonov AS, Sukhanov SV, Barsukov LI, Arseniev AS, Ovchinnikova TV (2011). Molecular mechanism of action of β-Hairpin antimicrobial peptide arenicin: Oligomeric structure in dodecylphosphocholine micelles and pore formation in planar lipid bilayers. Biochemistry 50 (28), 6255–6265
  26. Novgorodov SA, Wu BX, Gudz TI, Bielawski J, Ovchinnikova TV, Hannun YA, Obeid LM (2011). Novel pathway of ceramide production in mitochondria: Thioesterase and neutral ceramidase produce ceramide from sphingosine and acyl-CoA. J Biol Chem 286 (28), 25352–25362
  27. Salnikov ES, Aisenbrey C, Balandin SV, Maxim N Z, Ovchinnikova TV, Bechinger B (2011). Structure and alignment of the membrane-associated antimicrobial peptide arenicin by oriented solid-state nmr spectroscopy. Biochemistry 50 (18), 3784–3795
  28. MacHáň R, Hof M, Chernovets T, Zhmak MN, Ovchinnikova TV, Sýkora J (2011). Formation of arenicin-1 microdomains in bilayers and their specific lipid interaction revealed by Z-scan FCS. Anal Bioanal Chem 399 (10), 3547–3554
  29. Shenkarev ZO, Finkina EI, Nurmukhamedova EK, Balandin SV, Mineev KS, Nadezhdin KD, Yakimenko ZA, Tagaev AA, Temirov YV, Arseniev AS, Ovchinnikova TV (2010). Isolation, structure elucidation, and synergistic antibacterial activity of a novel two-component lantibiotic lichenicidin from bacillus licheniformis VK21. Biochemistry 49 (30), 6462–6472
  30. Stavrakoudis A, Tsoulos IG, Shenkarev ZO, Ovchinnikova TV (2009). Molecular dynamics simulation of antimicrobial peptide arenicin-2: β-hairpin stabilization by noncovalent interactions. Biospectroscopy 92 (3), 143–155
  31. Stegemann C, Kolobov A, Leonova YF, Knappe D, Shamova O, Ovchinnikova TV, Kokryakov VN, Hoffmann R (2009). Isolation, purification and de novo sequencing of TBD-1, the first beta-defensin from leukocytes of reptiles. Proteomics 9 (5), 1364–1373
  32. Finkina EI, Shramova EI, Tagaev AA, Ovchinnikova TV (2008). A novel defensin from the lentil Lens culinaris seeds. Biochem Biophys Res Commun 371 (4), 860–865
  33. Ovchinnikova TV, Shenkarev ZO, Balandin SV, Nadezhdin KD, Paramonov AS, Kokryakov VN, Arseniev AS (2008). Molecular insight into mechanism of antimicrobial action of the β-hairpin peptide arenicin: Specific oligomerization in detergent micelles. Biospectroscopy 89 (5), 455–464
  34. Ramazanova AS, Zavada LL, Starkov VG, Kovyazina IV, Subbotina TF, Kostyukhina EE, Dementieva IN, Ovchinnikova TV, Utkin YN (2008). Heterodimeric neurotoxic phospholipases A2-The first proteins from venom of recently established species Vipera nikolskii: Implication of venom composition in viper systematics. Toxicon 51 (4), 524–537
  35. Lyukmanova EN, Shenkarev ZO, Paramonov AS, Sobol AG, Ovchinnikova TV, Chupin VV, Kirpichnikov MP, Blommers MJJ, Arseniev AS (2008). Lipid-protein nanoscale bilayers: A versatile medium for NMR investigations of membrane proteins and membrane-active peptides. J Am Chem Soc 130 (7), 2140–2141
  36. Ovchinnikova TV, Shenkarev ZO, Nadezhdin KD, Balandin SV, Zhmak MN, Kudelina IA, Finkina EI, Kokryakov VN, Arseniev AS (2007). Recombinant expression, synthesis, purification, and solution structure of arenicin. Biochem Biophys Res Commun 360 (1), 156–162
  37. Ovchinnikova TV, Balandin SV, Aleshina GM, Tagaev AA, Leonova YF, Krasnodembsky ED, Menshenin AV, Kokryakov VN (2006). Aurelin, a novel antimicrobial peptide from jellyfish Aurelia aurita with structural features of defensins and channel-blocking toxins. Biochem Biophys Res Commun 348 (2), 514–523
  38. Raap J, Hollander J, Ovchinnikova TV, Swischeva NV, Skladnev D, Kiihne S (2006). Trans and surface membrane bound zervamicin IIB:13C-MAOSS-NMR at high spinning speed. J Biomol NMR 35 (4), 285–293
  39. Kropacheva TN, Salnikov ES, Nguyen HH, Reissmann S, Yakimenko ZA, Tagaev AA, Ovchinnikova TV, Raap J (2005). Membrane association and activity of 15/16-membered peptide antibiotics: Zervamicin IIB, ampullosporin A and antiamoebin I. BIOCHIM BIOPHYS ACTA 1715 (1), 6–18
  40. Shenkarev ZO, Paramonov AS, Balashova TA, Yakimenko ZA, Baru MB, Mustaeva LG, Raap J, Ovchinnikova TV, Arseniev AS (2004). High stability of the hinge region in the membrane-active peptide helix of zervamicin: Paramagnetic relaxation enhancement studies. Biochem Biophys Res Commun 325 (3), 1099–1105
  41. Ovchinnikova TV, Aleshina GM, Balandin SV, Krasnosdembskaya AD, Markelov ML, Frolova EI, Leonova YF, Tagaev AA, Krasnodembsky EG, Kokryakov VN (2004). Purification and primary structure of two isoforms of arenicin, a novel antimicrobial peptide from marine polychaeta Arenicola marina. FEBS Lett 577 (12), 209–214
  42. Shenkarev ZO, Balashova TA, Yakimenko ZA, Ovchinnikova TV, Arseniev AS (2004). Peptaibol zervamicin IIB structure and dynamics refinement from transhydrogen bond J couplings. Biophys J 86 (6), 3687–3699
  43. Vladimirova NM, Sautkina EN, Muraveva TI, Ovchinnikova TV, Potapenko NA (2003). Structural peculiarities of Na+,K+-ATPase isozymes from the calf brain. Bioorg Khim 29 (2), 146–158
  44. Karger EM, Frolova OY, Fedorova NV, Baratova LA, Ovchinnikova TV, Susi P, Makinen K, Ronnstrand L, Dorokhov YL, Atabekov JG (2003). Dysfunctionality of a tobacco mosaic virus movement protein mutant mimicking threonine 104 phosphorylation. J Gen Virol 84 (3), 727–732
  45. Zolotarev YA, Dadayan AK, Borisov YA, Dorokhova EM, Kozik VS, Vtyurin NN, Bocharov EV, Ziganshin RN, Lunina NA, Kostrov SV, Ovchinnikova TV, Myasoedov NF (2003). The effect of three-dimensional structure on the solid state isotope exchange of hydrogen in polypeptides with spillover hydrogen. Bioorg Chem 31 (6), 453–463
  46. Krachkovskii SA, Sobol AG, Ovchinnikova TV, Tagaev AA, Yakimenko ZA, Azizbekyan RR, Kuznetsova NI, Shamshina TN, Arseniev AS (2002). Isolation, biological properties, and spatial structure of antibiotic loloatin A. Bioorg Khim 28 (4), 302
  47. Vasilyeva OV, Kolygo KB, Leonova YF, Potapenko NA, Ovchinnikova TV (2002). Domain structure and ATP-induced conformational changes in Escherichia coli protease Lon revealed by limited proteolysis and autolysis. FEBS Lett 526 (13), 66–70
  48. Milov AD, Tsvetkov YD, Gorbunova EY, Mustaeva LG, Ovchinnikova TV, Raap J (2002). Self-aggregation properties of spin-labeled zervamicin IIA as studied by PELDOR spectroscopy. Biospectroscopy 64 (6), 328–336
  49. Shenkarev ZO, Balashova TA, Efremov RG, Yakimenko ZA, Ovchinnikova TV, Raap J, Arseniev AS (2002). Spatial structure of zervamicin IIB bound to DPC micelles: Implications for voltage-gating. Biophys J 82 (2), 762–771
  50. Zaitseva LG, Ovchinnikova TV, Grinkevich VA (2001). Protein import into mitochondria. Bioorg Khim 26 (9), 658–661
  51. Bechinger B, Skladnev DA, Ogrel A, Li X, Rogozhkina EV, Ovchinnikova TV, ONeil JDJ, Raap J (2001). 15N and 31P solid-state NMR investigations on the orientation of zervamicin II and alamethicin in phosphatidylcholine membranes. Biochemistry 40 (31), 9428–9437
  52. Korzhnev DM, Bocharov EV, Zhuravlyova AV, Orekhov VY, Ovchinnikova TV, Billeter M, Arseniev AS (2001). Backbone dynamics of the channel-forming antibiotic zervamicin IIB studied by15N NMR relaxation. FEBS Lett 495 (12), 52–55
  53. Zaitseva LG, Ovchinnikova TV, Grinkevich VA (2000). Protein import into mitochondria. Bioorg Khim 26 (9), 643–661
  54. Kukhtina VV, Weise C, Osipov AV, Starkov VG, Titov MI, Esipov SE, Ovchinnikova TV, Tsetlin VI, Utkin YN (2000). The MALDI mass spectrometry in the identification of new proteins in snake venoms. Bioorg Khim 26 (11), 803–807
  55. Balashova TA, Shenkarev ZO, Tagaev AA, Ovchinnikova TV, Raap J, Arseniev AS (2000). NMR structure of the channel-former zervamicin IIB in isotropic solvents. FEBS Lett 466 (23), 333–336
  56. Shkarenkova LS, Orlovskaya TT, Ovchinnikova TV (1998). Informational Support for Research in Biotechnology (Analytical Review). Bioorg Khim 24 (1), 80
  57. Vladimirova NM, Muraveva TI, Ovchinnikova TV, Potapenko NA, Khodova OM (1998). Na+,K+-ATPase isozymes in the bovine brain grey matter and brain stem. Cancer Biol Med 12 (3), 435–439
  58. Telezhinskaya IN, Ovchinnikova TV (1998). Molecular Sequence Databases in the Field of Bioorganic Chemistry (Analytical Review). Bioorg Khim 24 (5), 398–400
  59. Shkarenkova LS, Orlovskaya TT, Ovchinnikova TV (1997). Scientific Informational Support for Research in Physicochemical Biology (Analytical Review). Bioorg Khim 23 (2), 157–158