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• Liquid but Durable: Molecular Dynamics Explains Unique Character of Archaeal Biomembranes December 12, 2014

  Archaea, initially known as archaebacteria, mostly are extremophiles: they thrive environments of high temperature, pressure, salinity and acidity. Probably, “special path” of archaea was predestined by unique properties of their membranes, which significantly differ from bacterial and eukaryotic ones. In Laboratory of biomolecular modeling at IBCh, Russian Academy of Sciences, a computational study was conducted to discover relationship between chemical structure of archaeal lipids and physical properties of the membranes. The work was published in Scientific Reports.

• Ganglioside GD2 as a Key Tool Towards Novel Anti-Cancer Therapy November 27, 2014

  Besides proteins, glycosphingolipids and in particularly ganglioside GD2 can be treated as targets for anti-cancer therapy. It has been discovered that classic immune antitumor mechanisms are not exclusive (and probably are not the main) reasons of therapeutic activity of GD2-specific antibodies. In the study, carried out in the Group of molecular modulators of immunity in IBCh RAS, at the first time was proved unique property of ganglioside GD2 to activate “suicide” of tumor cells after it binding with GD2-specific antibodies. The project aimed to develop new anticancer drugs based on this study recently has received approval by the Skolkovo Foundation.

• Nadya Pletneva won the L'Oréal-UNESCO Award for Women in Science November 26, 2014

  Our congratulations to Nadya and her coworkers on this remarkable achievement! The award aims to improve the position of women in science by recognizing outstanding women researchers.

• Сalculations with Nanoscale Smart Particles August 21, 2014

  Researchers from the Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Institute of General Physics of the Russian Academy of Sciences, and Moscow Institute of Physics and Technology have made an important step towards creating medical nanorobots. They discovered a way of enabling nano- and microparticles to produce logical calculations using a variety of biochemical reactions. Details of their research project are given in the journal Nature Nanotechnology.

• Novel luciferin from Siberian bioluminescent worm April 16, 2014

  The structure of a novel luciferin was determined for the first time in the last 25 years as a result of collaboration between groups from IBCh RAS (Moscow) and IBP SB RAS (Krasnoyarsk) — results published in Angewandte Chemie IntEd.