Russ. J. Bioorganic Chem., 2022, 48(6):1362–1366

CycloOctaTetraene as a Photostabilizer of Fast Protein Fluorogen

We report two new analogs of the N871b fluorogen that contain CycloOctaTetraene. We have studied the photostability of fluorescent complexes of the FAST protein with new compounds by confocal microscopy when staining living HeLa Kyoto cells. One of the new analogs exhibits a higher photostability in the complex with FAST than the previously published N871b fluorogen. The results indicate that cyclooctatetraene is a highly promising compound for the modification of dyes based on arylidene imidazolones.

Sokolov AI, Gorshkova AA, Baleeva NS, Baranov MS

Laboratory of genetically encoded molecular tools, Group of chemistry of heterocyclic compounds

: 10.1134/S1068162022060231
Scopus: 2-s2.0-85144522259
IBCH: 10399
Ссылка на статью в журнале: https://link.springer.com/article/10.1134/S1068162022060231
Кол-во цитирований на 02.2024: 0
Данные статьи проверены модераторами 2022-12-24

Список научных проектов, где отмечена публикация

  1. -Разработка новых молекулярных инструментов ферментативного и флуорогенного флуоресцентного мечения для прижизненной визуализации в живых системах (July 1, 2018 — June 30, 2023). Baranov M.S., Baleeva N.S., Goncharuk S.A., Myasnyanko I.N., Smirnov A.Y.. Grant, RSF.