Isolation, biological properties, and spatial structure of antibiotic loloatin A
A peptide antibiotic with cyanolytic activity was isolated from the IGM52 strain of the Brevibacillus laterosporus Gram-positive spore-forming bacteria. By1H NMR spectroscopy, this antibiotic was identified as loloatin A, a cyclic decapeptide cyclo(-Asn-Asp-Tyr-Val-Orn-Leu-D-Tyr-Pro-Phe-D-Phe-). The spatial structure of loloatin A in solution was determined.